Sossey-Alaoui K - Search Results

1

Targeted Deletion of Kindlin-2 in Mouse Mammary Glands Inhibits Tumor Growth, Invasion, and Metastasis Downstream of a TGF-β/EGF Oncogenic Signaling Pathway.

Wang W, Rana PS, Alkrekshi A, Bialkowska K, Markovic V, Schiemann WP, Plow EF, Pluskota E, Sossey-Alaoui K. Wang W, et al. Cancers (Basel). 2022 Jan 27;14(3):639. doi: 10.3390/cancers14030639. Cancers (Basel). 2022. PMID: 35158908 Free PMC article.

2

The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion.

Sossey-Alaoui K, Bialkowska K, Plow EF. Sossey-Alaoui K, et al. J Biol Chem. 2009 Nov 27;284(48):33019-29. doi: 10.1074/jbc.M109.034553. Epub 2009 Oct 1. J Biol Chem. 2009. PMID: 19801681 Free PMC article.

3

The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell.

Bialkowska K, Ma YQ, Bledzka K, Sossey-Alaoui K, Izem L, Zhang X, Malinin N, Qin J, Byzova T, Plow EF. Bialkowska K, et al. J Biol Chem. 2010 Jun 11;285(24):18640-9. doi: 10.1074/jbc.M109.085746. Epub 2010 Apr 8. J Biol Chem. 2010. PMID: 20378539 Free PMC article.

4

WAVE3, an actin remodeling protein, is regulated by the metastasis suppressor microRNA, miR-31, during the invasion-metastasis cascade.

Sossey-Alaoui K, Downs-Kelly E, Das M, Izem L, Tubbs R, Plow EF. Sossey-Alaoui K, et al. Int J Cancer. 2011 Sep 15;129(6):1331-43. doi: 10.1002/ijc.25793. Epub 2011 Mar 22. Int J Cancer. 2011. PMID: 21105030 Free PMC article.

5

miR-31 is a broad regulator of β1-integrin expression and function in cancer cells.

Augoff K, Das M, Bialkowska K, McCue B, Plow EF, Sossey-Alaoui K. Augoff K, et al. Mol Cancer Res. 2011 Nov;9(11):1500-8. doi: 10.1158/1541-7786.MCR-11-0311. Epub 2011 Aug 29. Mol Cancer Res. 2011. PMID: 21875932 Free PMC article.

6

miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer.

Augoff K, McCue B, Plow EF, Sossey-Alaoui K. Augoff K, et al. Mol Cancer. 2012 Jan 30;11:5. doi: 10.1186/1476-4598-11-5. Mol Cancer. 2012. PMID: 22289355 Free PMC article.

7

TGF-β upregulates miR-181a expression to promote breast cancer metastasis.

Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP. Taylor MA, et al. J Clin Invest. 2013 Jan;123(1):150-63. doi: 10.1172/JCI64946. Epub 2012 Dec 17. J Clin Invest. 2013. PMID: 23241956 Free PMC article. Clinical Trial.

8

Upregulated WAVE3 expression is essential for TGF-β-mediated EMT and metastasis of triple-negative breast cancer cells.

Taylor MA, Davuluri G, Parvani JG, Schiemann BJ, Wendt MK, Plow EF, Schiemann WP, Sossey-Alaoui K. Taylor MA, et al. Breast Cancer Res Treat. 2013 Nov;142(2):341-53. doi: 10.1007/s10549-013-2753-1. Epub 2013 Nov 7. Breast Cancer Res Treat. 2013. PMID: 24197660 Free PMC article.

9

Kindlin-3 enhances breast cancer progression and metastasis by activating Twist-mediated angiogenesis.

Sossey-Alaoui K, Pluskota E, Davuluri G, Bialkowska K, Das M, Szpak D, Lindner DJ, Downs-Kelly E, Thompson CL, Plow EF. Sossey-Alaoui K, et al. FASEB J. 2014 May;28(5):2260-71. doi: 10.1096/fj.13-244004. Epub 2014 Jan 27. FASEB J. 2014. PMID: 24469992 Free PMC article.

10

Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers.

Wendt MK, Taylor MA, Schiemann BJ, Sossey-Alaoui K, Schiemann WP. Wendt MK, et al. Breast Cancer Res. 2014 Mar 11;16(2):R24. doi: 10.1186/bcr3623. Breast Cancer Res. 2014. PMID: 24618085 Free PMC article.

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