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Page 1
Germinal centre-driven maturation of B cell response to mRNA vaccination.
Kim W, Zhou JQ, Horvath SC, Schmitz AJ, Sturtz AJ, Lei T, Liu Z, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Whelan SPJ, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: sturtz aj. Nature. 2022 Apr;604(7904):141-145. doi: 10.1038/s41586-022-04527-1. Epub 2022 Feb 15. Nature. 2022. PMID: 35168246 Free PMC article.
Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria.
Vijay R, Guthmiller JJ, Sturtz AJ, Surette FA, Rogers KJ, Sompallae RR, Li F, Pope RL, Chan JA, de Labastida Rivera F, Andrew D, Webb L, Maury WJ, Xue HH, Engwerda CR, McCarthy JS, Boyle MJ, Butler NS. Vijay R, et al. Among authors: sturtz aj. Nat Immunol. 2020 Jul;21(7):790-801. doi: 10.1038/s41590-020-0678-5. Epub 2020 May 18. Nat Immunol. 2020. PMID: 32424361 Free PMC article. Clinical Trial.
Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination.
Kim W, Zhou JQ, Sturtz AJ, Horvath SC, Schmitz AJ, Lei T, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Middleton WD, Teefey SA, Pusic I, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Kim W, et al. Among authors: sturtz aj. bioRxiv [Preprint]. 2021 Nov 2:2021.10.31.466651. doi: 10.1101/2021.10.31.466651. bioRxiv. 2021. Update in: Nature. 2022 Apr;604(7904):141-145. doi: 10.1038/s41586-022-04527-1. PMID: 34751268 Free PMC article. Updated. Preprint.
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, Parra-Rodriguez L, Nachbagauer R, Nestorova B, Chalkias S, Farnsworth CW, Klebert MK, Pusic I, Strnad BS, Middleton WD, Teefey SA, Whelan SPJ, Diamond MS, Paris R, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Alsoussi WB, et al. Among authors: sturtz aj. bioRxiv [Preprint]. 2022 Sep 22:2022.09.22.509040. doi: 10.1101/2022.09.22.509040. bioRxiv. 2022. Update in: Nature. 2023 May;617(7961):592-598. doi: 10.1038/s41586-023-06025-4. PMID: 36172127 Free PMC article. Updated. Preprint.
SARS-CoV-2 Omicron boosting induces de novo B cell response in humans.
Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, Mirza SF, Parra-Rodriguez L, Nachbagauer R, Nestorova B, Chalkias S, Farnsworth CW, Klebert MK, Pusic I, Strnad BS, Middleton WD, Teefey SA, Whelan SPJ, Diamond MS, Paris R, O'Halloran JA, Presti RM, Turner JS, Ellebedy AH. Alsoussi WB, et al. Among authors: sturtz aj. Nature. 2023 May;617(7961):592-598. doi: 10.1038/s41586-023-06025-4. Epub 2023 Apr 3. Nature. 2023. PMID: 37011668
CD4+ T cells exhibit distinct transcriptional phenotypes in the lymph nodes and blood following mRNA vaccination in humans.
Borcherding N, Kim W, Quinn M, Han F, Zhou JQ, Sturtz AJ, Schmitz AJ, Lei T, Schattgen SA, Klebert MK, Suessen T, Middleton WD, Goss CW, Liu C, Crawford JC, Thomas PG, Teefey SA, Presti RM, O'Halloran JA, Turner JS, Ellebedy AH, Mudd PA. Borcherding N, et al. Among authors: sturtz aj. Nat Immunol. 2024 Sep;25(9):1731-1741. doi: 10.1038/s41590-024-01888-9. Epub 2024 Aug 20. Nat Immunol. 2024. PMID: 39164479
Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.
Surette FA, Guthmiller JJ, Li L, Sturtz AJ, Vijay R, Pope RL, McClellan BL, Pack AD, Zander RA, Shao P, Lan LY, Fernandez-Ruiz D, Heath WR, Wilson PC, Butler NS. Surette FA, et al. Among authors: sturtz aj. PLoS Pathog. 2021 Feb 2;17(2):e1009288. doi: 10.1371/journal.ppat.1009288. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33529242 Free PMC article.
Adenoviral vectors infect B lymphocytes in vivo.
Rice-Boucher PJ, Mendonça SA, Alvarez AB, Sturtz AJ, Lorincz R, Dmitriev IP, Kashentseva EA, Lu ZH, Romano R, Selby M, Pingale K, Curiel DT. Rice-Boucher PJ, et al. Among authors: sturtz aj. Mol Ther. 2023 Sep 6;31(9):2600-2611. doi: 10.1016/j.ymthe.2023.07.004. Epub 2023 Jul 14. Mol Ther. 2023. PMID: 37452494 Free PMC article.