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Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint.
Grieshaber-Bouyer R, Exner T, Hackert NS, Radtke FA, Jelinsky SA, Halyabar O, Wactor A, Karimizadeh E, Brennan J, Schettini J, Jonsson H, Rao DA, Henderson LA, Müller-Tidow C, Lorenz HM, Wabnitz G, Lederer JA, Hadjipanayis A, Nigrovic PA. Grieshaber-Bouyer R, et al. Ann Rheum Dis. 2022 Jun;81(6):805-814. doi: 10.1136/annrheumdis-2021-221866. Epub 2022 Feb 15. Ann Rheum Dis. 2022. PMID: 35168946 Free PMC article.
Maestro endothelium conducts the neutrophils.
Grieshaber-Bouyer R, Nigrovic PA. Grieshaber-Bouyer R, et al. Blood. 2018 Oct 25;132(17):1734-1735. doi: 10.1182/blood-2018-09-872085. Blood. 2018. PMID: 30361462 Free PMC article.
IL-1β-driven osteoclastogenic Tregs accelerate bone erosion in arthritis.
Levescot A, Chang MH, Schnell J, Nelson-Maney N, Yan J, Martínez-Bonet M, Grieshaber-Bouyer R, Lee PY, Wei K, Blaustein RB, Morris A, Wactor A, Iwakura Y, Lederer JA, Rao DA, Charles JF, Nigrovic PA. Levescot A, et al. J Clin Invest. 2021 Sep 15;131(18):e141008. doi: 10.1172/JCI141008. J Clin Invest. 2021. PMID: 34343136 Free PMC article.
Arthritis flares mediated by tissue-resident memory T cells in the joint.
Chang MH, Levescot A, Nelson-Maney N, Blaustein RB, Winden KD, Morris A, Wactor A, Balu S, Grieshaber-Bouyer R, Wei K, Henderson LA, Iwakura Y, Clark RA, Rao DA, Fuhlbrigge RC, Nigrovic PA. Chang MH, et al. Cell Rep. 2021 Oct 26;37(4):109902. doi: 10.1016/j.celrep.2021.109902. Cell Rep. 2021. PMID: 34706228 Free PMC article.
Inflammation induces pro-NETotic neutrophils via TNFR2 signaling.
Neuenfeldt F, Schumacher JC, Grieshaber-Bouyer R, Habicht J, Schröder-Braunstein J, Gauss A, Merle U, Niesler B, Heineken N, Dalpke A, Gaida MM, Giese T, Meuer S, Samstag Y, Wabnitz G. Neuenfeldt F, et al. Cell Rep. 2022 Apr 19;39(3):110710. doi: 10.1016/j.celrep.2022.110710. Cell Rep. 2022. PMID: 35443164 Free article.
27 results