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Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain.
Hasegawa K, Ikeda S, Yaga M, Watanabe K, Urakawa R, Iehara A, Iwai M, Hashiguchi S, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Yoshihara S, Manabe M, Ichihara H, Mugitani A, Aoyama Y, Nakao T, Hirose A, Hino M, Ueda S, Takenaka K, Masuko T, Akashi K, Maruno T, Uchiyama S, Takamatsu S, Wada N, Morii E, Nagamori S, Motooka D, Kanai Y, Oji Y, Nakagawa T, Kijima N, Kishima H, Ikeda A, Ogino T, Shintani Y, Kubo T, Mihara E, Yusa K, Sugiyama H, Takagi J, Miyoshi E, Kumanogoh A, Hosen N. Hasegawa K, et al. Among authors: ikeda s, ikeda a. Sci Transl Med. 2022 Feb 16;14(632):eaax7706. doi: 10.1126/scitranslmed.aax7706. Epub 2022 Feb 16. Sci Transl Med. 2022. PMID: 35171652
Identification of glioblastoma-specific antigens expressed in patient-derived tumor cells as candidate targets for chimeric antigen receptor T cell therapy.
Nakagawa T, Kijima N, Hasegawa K, Ikeda S, Yaga M, Wibowo T, Tachi T, Kuroda H, Hirayama R, Okita Y, Kinoshita M, Kagawa N, Kanemura Y, Hosen N, Kishima H. Nakagawa T, et al. Among authors: ikeda s. Neurooncol Adv. 2022 Nov 15;5(1):vdac177. doi: 10.1093/noajnl/vdac177. eCollection 2023 Jan-Dec. Neurooncol Adv. 2022. PMID: 36601313 Free PMC article.
CD98 heavy chain protein is overexpressed in non-small cell lung cancer and is a potential target for CAR T-cell therapy.
Yaga M, Hasegawa K, Ikeda S, Matsubara M, Hiroshima T, Kimura T, Shirai Y, Tansri W, Uehara H, Tachikawa M, Okairi Y, Sone M, Mori H, Kogue Y, Akamine H, Okuzaki D, Kawagishi K, Kawanaka S, Yamato H, Takeuchi Y, Okura E, Kanzaki R, Okami J, Nakamichi I, Nakane S, Kobayashi A, Iwazawa T, Tokunaga T, Yokouchi H, Yano Y, Uchida J, Mori M, Komuta K, Tachi T, Kuroda H, Kijima N, Kishima H, Ichii M, Futami S, Naito Y, Shiroyama T, Miyake K, Koyama S, Hirata H, Takeda Y, Funaki S, Shintani Y, Kumanogoh A, Hosen N. Yaga M, et al. Among authors: ikeda s. Sci Rep. 2024 Aug 2;14(1):17917. doi: 10.1038/s41598-024-68779-9. Sci Rep. 2024. PMID: 39095551 Free PMC article.
CAR-NK cells derived from cord blood originate mainly from CD56-CD7+CD34-HLA-DR-Lin- NK progenitor cells.
Wibowo T, Kogue Y, Ikeda S, Yaga M, Tachikawa M, Suga M, Kida S, Shibata K, Tsutsumi K, Murakami H, Ueda Y, Kato H, Fukushima K, Fujita J, Ueda T, Kusakabe S, Hino A, Ichii M, Imai C, Okuzaki D, Kumanogoh A, Hosen N. Wibowo T, et al. Among authors: ikeda s. Mol Ther Methods Clin Dev. 2024 Nov 12;32(4):101374. doi: 10.1016/j.omtm.2024.101374. eCollection 2024 Dec 12. Mol Ther Methods Clin Dev. 2024. PMID: 39659759 Free PMC article.
4,562 results