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Germline and Somatic Smoothened Mutations in Non-Small-Cell Lung Cancer Are Potentially Responsive to Hedgehog Inhibitor Vismodegib.
Tsao AS, Wistuba I, Xia D, Byers L, Diao L, Wang J, Papadimitrakopoulou V, Tang X, Lu W, Kadara H, Grigoryev DN, Selvan ME, Gümüş ZH, Tan Z, Zhang S, Nilsson M, Heymach JV. Tsao AS, et al. Among authors: zhang s. JCO Precis Oncol. 2017 Nov;1:1-10. doi: 10.1200/PO.17.00149. JCO Precis Oncol. 2017. PMID: 35172522 No abstract available.
Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.
Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, Tsao A, Liu S, Larsen JE, Wang J, Diao L, Coombes KR, Chen L, Zhang S, Abdelmelek MF, Tang X, Papadimitrakopoulou V, Minna JD, Lippman SM, Hong WK, Herbst RS, Wistuba II, Heymach JV, Powis G. Ihle NT, et al. Among authors: zhang s. J Natl Cancer Inst. 2012 Feb 8;104(3):228-39. doi: 10.1093/jnci/djr523. Epub 2012 Jan 13. J Natl Cancer Inst. 2012. PMID: 22247021 Free PMC article.
Computational polypharmacology: a new paradigm for drug discovery.
Chaudhari R, Tan Z, Huang B, Zhang S. Chaudhari R, et al. Among authors: zhang s. Expert Opin Drug Discov. 2017 Mar;12(3):279-291. doi: 10.1080/17460441.2017.1280024. Epub 2017 Jan 23. Expert Opin Drug Discov. 2017. PMID: 28067061 Free PMC article. Review.
Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer.
Robichaux JP, Elamin YY, Tan Z, Carter BW, Zhang S, Liu S, Li S, Chen T, Poteete A, Estrada-Bernal A, Le AT, Truini A, Nilsson MB, Sun H, Roarty E, Goldberg SB, Brahmer JR, Altan M, Lu C, Papadimitrakopoulou V, Politi K, Doebele RC, Wong KK, Heymach JV. Robichaux JP, et al. Among authors: zhang s. Nat Med. 2018 May;24(5):638-646. doi: 10.1038/s41591-018-0007-9. Epub 2018 Apr 23. Nat Med. 2018. PMID: 29686424 Free PMC article.
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