Hussack G - Search Results

1

Targeting insulin-like growth factor-1 receptor (IGF1R) for brain delivery of biologics.

Alata W, Yogi A, Brunette E, Delaney CE, van Faassen H, Hussack G, Iqbal U, Kemmerich K, Haqqani AS, Moreno MJ, Stanimirovic DB. Alata W, et al. Among authors: hussack g. FASEB J. 2022 Mar;36(3):e22208. doi: 10.1096/fj.202101644R. FASEB J. 2022. PMID: 35192204

2

Neutralization of Clostridium difficile toxin A with single-domain antibodies targeting the cell receptor binding domain.

Hussack G, Arbabi-Ghahroudi M, van Faassen H, Songer JG, Ng KK, MacKenzie R, Tanha J. Hussack G, et al. J Biol Chem. 2011 Mar 18;286(11):8961-76. doi: 10.1074/jbc.M110.198754. Epub 2011 Jan 7. J Biol Chem. 2011. PMID: 21216961 Free PMC article.

3

A V(L) single-domain antibody library shows a high-propensity to yield non-aggregating binders.

Hussack G, Keklikian A, Alsughayyir J, Hanifi-Moghaddam P, Arbabi-Ghahroudi M, van Faassen H, Hou ST, Sad S, MacKenzie R, Tanha J. Hussack G, et al. Protein Eng Des Sel. 2012 Jun;25(6):313-8. doi: 10.1093/protein/gzs014. Epub 2012 Apr 6. Protein Eng Des Sel. 2012. PMID: 22490957

4

Protease-resistant single-domain antibodies inhibit Campylobacter jejuni motility.

Hussack G, Riazi A, Ryan S, van Faassen H, MacKenzie R, Tanha J, Arbabi-Ghahroudi M. Hussack G, et al. Protein Eng Des Sel. 2014 Jun;27(6):191-8. doi: 10.1093/protein/gzu011. Epub 2014 Apr 16. Protein Eng Des Sel. 2014. PMID: 24742504

5

Targeting surface-layer proteins with single-domain antibodies: a potential therapeutic approach against Clostridium difficile-associated disease.

Kandalaft H, Hussack G, Aubry A, van Faassen H, Guan Y, Arbabi-Ghahroudi M, MacKenzie R, Logan SM, Tanha J. Kandalaft H, et al. Among authors: hussack g. Appl Microbiol Biotechnol. 2015 Oct;99(20):8549-62. doi: 10.1007/s00253-015-6594-1. Epub 2015 May 5. Appl Microbiol Biotechnol. 2015. PMID: 25936376 Free PMC article.

6

A Rational Engineering Strategy for Designing Protein A-Binding Camelid Single-Domain Antibodies.

Henry KA, Sulea T, van Faassen H, Hussack G, Purisima EO, MacKenzie CR, Arbabi-Ghahroudi M. Henry KA, et al. Among authors: hussack g. PLoS One. 2016 Sep 15;11(9):e0163113. doi: 10.1371/journal.pone.0163113. eCollection 2016. PLoS One. 2016. PMID: 27631624 Free PMC article.

7

A disulfide-stabilized human V_L single-domain antibody library is a source of soluble and highly thermostable binders.

Henry KA, Kandalaft H, Lowden MJ, Rossotti MA, van Faassen H, Hussack G, Durocher Y, Kim DY, Tanha J. Henry KA, et al. Among authors: hussack g. Mol Immunol. 2017 Oct;90:190-196. doi: 10.1016/j.molimm.2017.07.006. Epub 2017 Aug 15. Mol Immunol. 2017. PMID: 28820969

8

A Novel Affinity Tag, ABTAG, and Its Application to the Affinity Screening of Single-Domain Antibodies Selected by Phage Display.

Hussack G, Baral TN, Baardsnes J, van Faassen H, Raphael S, Henry KA, Zhang J, MacKenzie CR. Hussack G, et al. Front Immunol. 2017 Oct 30;8:1406. doi: 10.3389/fimmu.2017.01406. eCollection 2017. Front Immunol. 2017. PMID: 29163485 Free PMC article.

9

Camelid single-domain antibodies raised by DNA immunization are potent inhibitors of EGFR signaling.

Rossotti MA, Henry KA, van Faassen H, Tanha J, Callaghan D, Hussack G, Arbabi-Ghahroudi M, MacKenzie CR. Rossotti MA, et al. Among authors: hussack g. Biochem J. 2019 Jan 7;476(1):39-50. doi: 10.1042/BCJ20180795. Biochem J. 2019. PMID: 30455372

10

Neutralization of Clostridium difficile toxin B with VHH-Fc fusions targeting the delivery and CROPs domains.

Hussack G, Ryan S, van Faassen H, Rossotti M, MacKenzie CR, Tanha J. Hussack G, et al. PLoS One. 2018 Dec 12;13(12):e0208978. doi: 10.1371/journal.pone.0208978. eCollection 2018. PLoS One. 2018. PMID: 30540857 Free PMC article.

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