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GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Among authors: li y. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
The many lives of Myc in the pancreatic β-cell.
Rosselot C, Baumel-Alterzon S, Li Y, Brill G, Lambertini L, Katz LS, Lu G, Garcia-Ocaña A, Scott DK. Rosselot C, et al. Among authors: li y. J Biol Chem. 2021 Jan-Jun;296:100122. doi: 10.1074/jbc.REV120.011149. Epub 2020 Dec 2. J Biol Chem. 2021. PMID: 33239359 Free PMC article. Review.
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system.
Rosselot C, Li Y, Wang P, Alvarsson A, Beliard K, Lu G, Kang R, Li R, Liu H, Gillespie V, Tzavaras N, Kumar K, DeVita RJ, Stewart AF, Stanley SA, Garcia-Ocaña A. Rosselot C, et al. Among authors: li y, li r. Sci Transl Med. 2024 Jul 10;16(755):eadg3456. doi: 10.1126/scitranslmed.adg3456. Epub 2024 Jul 10. Sci Transl Med. 2024. PMID: 38985854
239,133 results
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