Sun H - Search Results

1

Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4⁺ T Cells.

Lagarrigue F, Tan B, Du Q, Fan Z, Lopez-Ramirez MA, Gingras AR, Wang H, Qi W, Sun H. Lagarrigue F, et al. Among authors: sun h. J Immunol. 2022 Mar 15;208(6):1378-1388. doi: 10.4049/jimmunol.2100843. Epub 2022 Feb 23. J Immunol. 2022. PMID: 35197328 Free PMC article.

2

Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development.

Sun H, Lagarrigue F, Gingras AR, Fan Z, Ley K, Ginsberg MH. Sun H, et al. J Cell Biol. 2018 Apr 2;217(4):1453-1465. doi: 10.1083/jcb.201707055. Epub 2018 Mar 13. J Cell Biol. 2018. PMID: 29535192 Free PMC article.

3

Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.

Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH. Lagarrigue F, et al. Among authors: sun h. Blood Adv. 2018 Sep 25;2(18):2358-2368. doi: 10.1182/bloodadvances.2018020487. Blood Adv. 2018. PMID: 30242097 Free PMC article.

4

High-Affinity Bent β₂-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis.

Fan Z, Kiosses WB, Sun H, Orecchioni M, Ghosheh Y, Zajonc DM, Arnaout MA, Gutierrez E, Groisman A, Ginsberg MH, Ley K. Fan Z, et al. Among authors: sun h. Cell Rep. 2019 Jan 2;26(1):119-130.e5. doi: 10.1016/j.celrep.2018.12.038. Cell Rep. 2019. PMID: 30605669 Free PMC article.

5

Frontline Science: A flexible kink in the transmembrane domain impairs β2 integrin extension and cell arrest from rolling.

Sun H, Fan Z, Gingras AR, Lopez-Ramirez MA, Ginsberg MH, Ley K. Sun H, et al. J Leukoc Biol. 2020 Feb;107(2):175-183. doi: 10.1002/JLB.1HI0219-073RR. Epub 2019 Sep 1. J Leukoc Biol. 2020. PMID: 31475386 Free PMC article.

6

β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25^hiFoxP3⁺ Regulatory T Cells.

Sun H, Kuk W, Rivera-Nieves J, Lopez-Ramirez MA, Eckmann L, Ginsberg MH. Sun H, et al. Cell Mol Gastroenterol Hepatol. 2020;9(3):369-385. doi: 10.1016/j.jcmgh.2019.10.012. Epub 2019 Nov 9. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31707128 Free PMC article.

7

Talin-1 is the principal platelet Rap1 effector of integrin activation.

Lagarrigue F, Paul DS, Gingras AR, Valadez AJ, Sun H, Lin J, Cuevas MN, Ablack JN, Lopez-Ramirez MA, Bergmeier W, Ginsberg MH. Lagarrigue F, et al. Among authors: sun h. Blood. 2020 Sep 3;136(10):1180-1190. doi: 10.1182/blood.2020005348. Blood. 2020. PMID: 32518959 Free PMC article.

8

Isolation and Purification of Mouse Brain Endothelial Cells to Study Cerebral Cavernous Malformation Disease.

Hale P, Soliman SI, Sun H, Lopez-Ramirez MA. Hale P, et al. Among authors: sun h. Methods Mol Biol. 2020;2152:139-150. doi: 10.1007/978-1-0716-0640-7_11. Methods Mol Biol. 2020. PMID: 32524550

9

Kindlin-3 recruitment to the plasma membrane precedes high-affinity β2-integrin and neutrophil arrest from rolling.

Wen L, Marki A, Roy P, McArdle S, Sun H, Fan Z, Gingras AR, Ginsberg MH, Ley K. Wen L, et al. Among authors: sun h. Blood. 2021 Jan 7;137(1):29-38. doi: 10.1182/blood.2019003446. Blood. 2021. PMID: 32777822 Free PMC article.

10

Distinct integrin activation pathways for effector and regulatory T cell trafficking and function.

Sun H, Lagarrigue F, Wang H, Fan Z, Lopez-Ramirez MA, Chang JT, Ginsberg MH. Sun H, et al. J Exp Med. 2021 Feb 1;218(2):e20201524. doi: 10.1084/jem.20201524. J Exp Med. 2021. PMID: 33104169 Free PMC article.

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