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Primary cilia defects causing mitral valve prolapse.
Toomer KA, Yu M, Fulmer D, Guo L, Moore KS, Moore R, Drayton KD, Glover J, Peterson N, Ramos-Ortiz S, Drohan A, Catching BJ, Stairley R, Wessels A, Lipschutz JH, Delling FN, Jeunemaitre X, Dina C, Collins RL, Brand H, Talkowski ME, Del Monte F, Mukherjee R, Awgulewitsch A, Body S, Hardiman G, Hazard ES, da Silveira WA, Wang B, Leyne M, Durst R, Markwald RR, Le Scouarnec S, Hagege A, Le Tourneau T, Kohl P, Rog-Zielinska EA, Ellinor PT, Levine RA, Milan DJ, Schott JJ, Bouatia-Naji N, Slaugenhaupt SA, Norris RA. Toomer KA, et al. Among authors: moore r, moore ks. Sci Transl Med. 2019 May 22;11(493):eaax0290. doi: 10.1126/scitranslmed.aax0290. Sci Transl Med. 2019. PMID: 31118289 Free PMC article.
Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis.
Fulmer D, Toomer K, Guo L, Moore K, Glover J, Moore R, Stairley R, Lobo G, Zuo X, Dang Y, Su Y, Fogelgren B, Gerard P, Chung D, Heydarpour M, Mukherjee R, Body SC, Norris RA, Lipschutz JH. Fulmer D, et al. Among authors: moore r, moore k. Circulation. 2019 Oct 15;140(16):1331-1341. doi: 10.1161/CIRCULATIONAHA.119.038376. Epub 2019 Aug 7. Circulation. 2019. PMID: 31387361 Free PMC article.
Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin.
Fulmer D, Toomer KA, Glover J, Guo L, Moore K, Moore R, Stairley R, Gensemer C, Abrol S, Rumph MK, Emetu F, Lipschutz JH, McDowell C, Bian J, Wang C, Beck T, Wessels A, Renault MA, Norris RA. Fulmer D, et al. Among authors: moore r, moore k. Dev Biol. 2020 Jul 1;463(1):26-38. doi: 10.1016/j.ydbio.2020.03.003. Epub 2020 Mar 6. Dev Biol. 2020. PMID: 32151560 Free PMC article.
PDGFRα: Expression and Function during Mitral Valve Morphogenesis.
Moore K, Fulmer D, Guo L, Koren N, Glover J, Moore R, Gensemer C, Beck T, Morningstar J, Stairley R, Norris RA. Moore K, et al. Among authors: moore r. J Cardiovasc Dev Dis. 2021 Mar 13;8(3):28. doi: 10.3390/jcdd8030028. J Cardiovasc Dev Dis. 2021. PMID: 33805717 Free PMC article.
DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.
Guo L, Beck T, Fulmer D, Ramos-Ortiz S, Glover J, Wang C, Moore K, Gensemer C, Morningstar J, Moore R, Schott JJ, Le Tourneau T, Koren N, Norris RA. Guo L, et al. Among authors: moore r, moore k. Dev Dyn. 2021 Oct;250(10):1432-1449. doi: 10.1002/dvdy.342. Epub 2021 Apr 9. Dev Dyn. 2021. PMID: 33811421 Free PMC article.
Mitral Valve Prolapse Induces Regionalized Myocardial Fibrosis.
Morningstar JE, Gensemer C, Moore R, Fulmer D, Beck TC, Wang C, Moore K, Guo L, Sieg F, Nagata Y, Bertrand P, Spampinato RA, Glover J, Poelzing S, Gourdie RG, Watts K, Richardson WJ, Levine RA, Borger MA, Norris RA. Morningstar JE, et al. Among authors: moore r, moore k. J Am Heart Assoc. 2021 Dec 21;10(24):e022332. doi: 10.1161/JAHA.121.022332. Epub 2021 Dec 7. J Am Heart Assoc. 2021. PMID: 34873924 Free PMC article.
Abnormal Mechanics Relate to Myocardial Fibrosis and Ventricular Arrhythmias in Patients With Mitral Valve Prolapse.
Nagata Y, Bertrand PB, Baliyan V, Kochav J, Kagan RD, Ujka K, Alfraidi H, van Kampen A, Morningstar JE, Dal-Bianco JP, Melnitchouk S, Holmvang G, Borger MA, Moore R, Hua L, Sultana R, Calle PV, Yum B, Guerrero JL, Neilan TG, Picard MH, Kim J, Delling FN, Hung J, Norris RA, Weinsaft JW, Levine RA. Nagata Y, et al. Among authors: moore r. Circ Cardiovasc Imaging. 2023 Apr;16(4):e014963. doi: 10.1161/CIRCIMAGING.122.014963. Epub 2023 Apr 18. Circ Cardiovasc Imaging. 2023. PMID: 37071717 Free PMC article.
8,380 results