Pi WC - Search Results

1

EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis.

Wang J, Yu X, Gong W, Liu X, Park KS, Ma A, Tsai YH, Shen Y, Onikubo T, Pi WC, Allison DF, Liu J, Chen WY, Cai L, Roeder RG, Jin J, Wang GG. Wang J, et al. Among authors: pi wc. Nat Cell Biol. 2022 Mar;24(3):384-399. doi: 10.1038/s41556-022-00850-x. Epub 2022 Feb 24. Nat Cell Biol. 2022. PMID: 35210568 Free PMC article.

2

E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia.

Pi WC, Wang J, Shimada M, Lin JW, Geng H, Lee YL, Lu R, Li D, Wang GG, Roeder RG, Chen WY. Pi WC, et al. Blood. 2020 Jul 2;136(1):11-23. doi: 10.1182/blood.2019003312. Blood. 2020. PMID: 32276273 Free PMC article.

3

Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress.

Liao CC, Shankar S, Pi WC, Chang CC, Ahmed GR, Chen WY, Hsia KC. Liao CC, et al. Among authors: pi wc. EMBO Rep. 2020 Jul 3;21(7):e48324. doi: 10.15252/embr.201948324. Epub 2020 Jun 2. EMBO Rep. 2020. PMID: 32484313 Free PMC article.

4

Andrographolide and its fluorescent derivative inhibit the main proteases of 2019-nCoV and SARS-CoV through covalent linkage.

Shi TH, Huang YL, Chen CC, Pi WC, Hsu YL, Lo LC, Chen WY, Fu SL, Lin CH. Shi TH, et al. Among authors: pi wc. Biochem Biophys Res Commun. 2020 Dec 10;533(3):467-473. doi: 10.1016/j.bbrc.2020.08.086. Epub 2020 Aug 25. Biochem Biophys Res Commun. 2020. PMID: 32977949 Free PMC article.

5

BAHCC1 binds H3K27me3 via a conserved BAH module to mediate gene silencing and oncogenesis.

Fan H, Lu J, Guo Y, Li D, Zhang ZM, Tsai YH, Pi WC, Ahn JH, Gong W, Xiang Y, Allison DF, Geng H, He S, Diao Y, Chen WY, Strahl BD, Cai L, Song J, Wang GG. Fan H, et al. Among authors: pi wc. Nat Genet. 2020 Dec;52(12):1384-1396. doi: 10.1038/s41588-020-00729-3. Epub 2020 Nov 2. Nat Genet. 2020. PMID: 33139953 Free PMC article.

6

Mediator subunit MED1 is required for E2A-PBX1-mediated oncogenic transcription and leukemic cell growth.

Lee YL, Ito K, Pi WC, Lin IH, Chu CS, Malik S, Cheng IH, Chen WY, Roeder RG. Lee YL, et al. Among authors: pi wc. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e1922864118. doi: 10.1073/pnas.1922864118. Proc Natl Acad Sci U S A. 2021. PMID: 33542097 Free PMC article.

7

A PRC2-Kdm5b axis sustains tumorigenicity of acute myeloid leukemia.

Ren Z, Kim A, Huang YT, Pi WC, Gong W, Yu X, Qi J, Jin J, Cai L, Roeder RG, Chen WY, Wang GG. Ren Z, et al. Among authors: pi wc. Proc Natl Acad Sci U S A. 2022 Mar 1;119(9):e2122940119. doi: 10.1073/pnas.2122940119. Proc Natl Acad Sci U S A. 2022. PMID: 35217626 Free PMC article.

8

Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein.

Liao CC, Wang YS, Pi WC, Wang CH, Wu YM, Chen WY, Hsia KC. Liao CC, et al. Among authors: pi wc. Nat Commun. 2023 Sep 8;14(1):5518. doi: 10.1038/s41467-023-41206-9. Nat Commun. 2023. PMID: 37684250 Free PMC article.

9

TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes.

Cheng IH, Pi WC, Hsu CH, Guo Y, Lai JL, Wang GG, Chung BC, Roeder RG, Chen WY. Cheng IH, et al. Among authors: pi wc. Cell Death Discov. 2024 May 21;10(1):244. doi: 10.1038/s41420-024-02017-z. Cell Death Discov. 2024. PMID: 38773077 Free PMC article.

10

Heterogeneous nuclear ribonucleoproteins A1 and A2 modulate expression of Tid1 isoforms and EGFR signaling in non-small cell lung cancer.

Chen CY, Jan CI, Pi WC, Wang WL, Yang PC, Wang TH, Karni R, Wang TC. Chen CY, et al. Among authors: pi wc. Oncotarget. 2016 Mar 29;7(13):16760-72. doi: 10.18632/oncotarget.7606. Oncotarget. 2016. PMID: 26919236 Free PMC article.

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