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Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations.
Miller TE, Lareau CA, Verga JA, DePasquale EAK, Liu V, Ssozi D, Sandor K, Yin Y, Ludwig LS, El Farran CA, Morgan DM, Satpathy AT, Griffin GK, Lane AA, Love JC, Bernstein BE, Sankaran VG, van Galen P. Miller TE, et al. Among authors: griffin gk. Nat Biotechnol. 2022 Jul;40(7):1030-1034. doi: 10.1038/s41587-022-01210-8. Epub 2022 Feb 24. Nat Biotechnol. 2022. PMID: 35210612 Free PMC article.
Blastic Plasmacytoid Dendritic Cell Neoplasm Is Dependent on BCL2 and Sensitive to Venetoclax.
Montero J, Stephansky J, Cai T, Griffin GK, Cabal-Hierro L, Togami K, Hogdal LJ, Galinsky I, Morgan EA, Aster JC, Davids MS, LeBoeuf NR, Stone RM, Konopleva M, Pemmaraju N, Letai A, Lane AA. Montero J, et al. Among authors: griffin gk. Cancer Discov. 2017 Feb;7(2):156-164. doi: 10.1158/2159-8290.CD-16-0999. Epub 2016 Dec 16. Cancer Discov. 2017. PMID: 27986708 Free PMC article.
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.
van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE. van Galen P, et al. Among authors: griffin gk. Cell. 2019 Mar 7;176(6):1265-1281.e24. doi: 10.1016/j.cell.2019.01.031. Epub 2019 Feb 28. Cell. 2019. PMID: 30827681 Free PMC article.
High-definition spatial transcriptomics for in situ tissue profiling.
Vickovic S, Eraslan G, Salmén F, Klughammer J, Stenbeck L, Schapiro D, Äijö T, Bonneau R, Bergenstråhle L, Navarro JF, Gould J, Griffin GK, Borg Å, Ronaghi M, Frisén J, Lundeberg J, Regev A, Ståhl PL. Vickovic S, et al. Among authors: griffin gk. Nat Methods. 2019 Oct;16(10):987-990. doi: 10.1038/s41592-019-0548-y. Epub 2019 Sep 9. Nat Methods. 2019. PMID: 31501547 Free PMC article.
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity.
Griffin GK, Wu J, Iracheta-Vellve A, Patti JC, Hsu J, Davis T, Dele-Oni D, Du PP, Halawi AG, Ishizuka JJ, Kim SY, Klaeger S, Knudsen NH, Miller BC, Nguyen TH, Olander KE, Papanastasiou M, Rachimi S, Robitschek EJ, Schneider EM, Yeary MD, Zimmer MD, Jaffe JD, Carr SA, Doench JG, Haining WN, Yates KB, Manguso RT, Bernstein BE. Griffin GK, et al. Nature. 2021 Jul;595(7866):309-314. doi: 10.1038/s41586-021-03520-4. Epub 2021 May 5. Nature. 2021. PMID: 33953401 Free PMC article.
Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis.
Togami K, Chung SS, Madan V, Booth CAG, Kenyon CM, Cabal-Hierro L, Taylor J, Kim SS, Griffin GK, Ghandi M, Li J, Li YY, Angelot-Delettre F, Biichle S, Seiler M, Buonamici S, Lovitch SB, Louissaint A Jr, Morgan EA, Jardin F, Piccaluga PP, Weinstock DM, Hammerman PS, Yang H, Konopleva M, Pemmaraju N, Garnache-Ottou F, Abdel-Wahab O, Koeffler HP, Lane AA. Togami K, et al. Among authors: griffin gk. Cancer Discov. 2022 Feb;12(2):522-541. doi: 10.1158/2159-8290.CD-20-1513. Epub 2021 Oct 6. Cancer Discov. 2022. PMID: 34615655 Free PMC article.
Distinction of lymphoid and myeloid clonal hematopoiesis.
Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, Bick AG, Uddin MM, Gibson CJ, Griffin GK, Honigberg MC, Zekavat SM, Paruchuri K, Natarajan P, Ebert BL. Niroula A, et al. Among authors: griffin gk. Nat Med. 2021 Nov;27(11):1921-1927. doi: 10.1038/s41591-021-01521-4. Epub 2021 Oct 18. Nat Med. 2021. PMID: 34663986 Free PMC article.
Single-Cell Multiomics Reveals Clonal T-Cell Expansions and Exhaustion in Blastic Plasmacytoid Dendritic Cell Neoplasm.
DePasquale EAK, Ssozi D, Ainciburu M, Good J, Noel J, Villanueva MA, Couturier CP, Shalek AK, Aranki SF, Mallidi HR, Griffin GK, Lane AA, van Galen P. DePasquale EAK, et al. Among authors: griffin gk. Front Immunol. 2022 Mar 10;13:809414. doi: 10.3389/fimmu.2022.809414. eCollection 2022. Front Immunol. 2022. PMID: 35359938 Free PMC article.
Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease.
Uddin MDM, Nguyen NQH, Yu B, Brody JA, Pampana A, Nakao T, Fornage M, Bressler J, Sotoodehnia N, Weinstock JS, Honigberg MC, Nachun D, Bhattacharya R, Griffin GK, Chander V, Gibbs RA, Rotter JI, Liu C, Baccarelli AA, Chasman DI, Whitsel EA, Kiel DP, Murabito JM, Boerwinkle E, Ebert BL, Jaiswal S, Floyd JS, Bick AG, Ballantyne CM, Psaty BM, Natarajan P, Conneely KN. Uddin MDM, et al. Among authors: griffin gk. Nat Commun. 2022 Sep 12;13(1):5350. doi: 10.1038/s41467-022-33093-3. Nat Commun. 2022. PMID: 36097025 Free PMC article.
77 results