Mallucci GR - Search Results

1

Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia.

Sidhom E, O'Brien JT, Butcher AJ, Smith HL, Mallucci GR, Underwood BR. Sidhom E, et al. Among authors: mallucci gr. Int J Mol Sci. 2022 Feb 11;23(4):2021. doi: 10.3390/ijms23042021. Int J Mol Sci. 2022. PMID: 35216136 Free PMC article. Review.

2

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy.

Halliday M, Mallucci GR. Halliday M, et al. Among authors: mallucci gr. Neuropharmacology. 2014 Jan;76 Pt A:169-74. doi: 10.1016/j.neuropharm.2013.08.034. Epub 2013 Sep 10. Neuropharmacology. 2014. PMID: 24035917 Review.

3

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice.

Moreno JA, Halliday M, Molloy C, Radford H, Verity N, Axten JM, Ortori CA, Willis AE, Fischer PM, Barrett DA, Mallucci GR. Moreno JA, et al. Among authors: mallucci gr. Sci Transl Med. 2013 Oct 9;5(206):206ra138. doi: 10.1126/scitranslmed.3006767. Sci Transl Med. 2013. PMID: 24107777

4

Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory.

Halliday M, Mallucci GR. Halliday M, et al. Among authors: mallucci gr. Neuropathol Appl Neurobiol. 2015 Jun;41(4):414-27. doi: 10.1111/nan.12211. Neuropathol Appl Neurobiol. 2015. PMID: 25556298 Free PMC article. Review.

5

PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia.

Radford H, Moreno JA, Verity N, Halliday M, Mallucci GR. Radford H, et al. Among authors: mallucci gr. Acta Neuropathol. 2015 Nov;130(5):633-42. doi: 10.1007/s00401-015-1487-z. Epub 2015 Oct 8. Acta Neuropathol. 2015. PMID: 26450683 Free PMC article.

6

The UPR and synaptic dysfunction in neurodegeneration.

Freeman OJ, Mallucci GR. Freeman OJ, et al. Among authors: mallucci gr. Brain Res. 2016 Oct 1;1648(Pt B):530-537. doi: 10.1016/j.brainres.2016.03.029. Epub 2016 Mar 26. Brain Res. 2016. PMID: 27021956 Review.

7

The unfolded protein response: mechanisms and therapy of neurodegeneration.

Smith HL, Mallucci GR. Smith HL, et al. Among authors: mallucci gr. Brain. 2016 Aug;139(Pt 8):2113-21. doi: 10.1093/brain/aww101. Epub 2016 May 11. Brain. 2016. PMID: 27190028 Free PMC article. Review.

8

M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss.

Bradley SJ, Bourgognon JM, Sanger HE, Verity N, Mogg AJ, White DJ, Butcher AJ, Moreno JA, Molloy C, Macedo-Hatch T, Edwards JM, Wess J, Pawlak R, Read DJ, Sexton PM, Broad LM, Steinert JR, Mallucci GR, Christopoulos A, Felder CC, Tobin AB. Bradley SJ, et al. Among authors: mallucci gr. J Clin Invest. 2017 Feb 1;127(2):487-499. doi: 10.1172/JCI87526. Epub 2016 Dec 19. J Clin Invest. 2017. PMID: 27991860 Free PMC article.

9

Repurposed drugs targeting eIF2α-P-mediated translational repression prevent neurodegeneration in mice.

Halliday M, Radford H, Zents KAM, Molloy C, Moreno JA, Verity NC, Smith E, Ortori CA, Barrett DA, Bushell M, Mallucci GR. Halliday M, et al. Among authors: mallucci gr. Brain. 2017 Jun 1;140(6):1768-1783. doi: 10.1093/brain/awx074. Brain. 2017. PMID: 28430857 Free PMC article.

10

The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway.

Hughes D, Mallucci GR. Hughes D, et al. Among authors: mallucci gr. FEBS J. 2019 Jan;286(2):342-355. doi: 10.1111/febs.14422. Epub 2018 Mar 11. FEBS J. 2019. PMID: 29476642 Free article. Review.

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