Asai A - Search Results

1

STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis.

Yanagimura N, Takeuchi S, Fukuda K, Arai S, Tanimoto A, Nishiyama A, Ogo N, Takahashi H, Asai A, Watanabe S, Kikuchi T, Yano S. Yanagimura N, et al. Among authors: asai a. NPJ Precis Oncol. 2022 Feb 28;6(1):11. doi: 10.1038/s41698-022-00254-y. NPJ Precis Oncol. 2022. PMID: 35228642 Free PMC article.

2

Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Ogo N, Oishi S, Matsuno K, Sawada J, Fujii N, Asai A. Ogo N, et al. Among authors: asai a. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3921-4. doi: 10.1016/j.bmcl.2007.04.101. Epub 2007 May 3. Bioorg Med Chem Lett. 2007. PMID: 17524640

3

Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors.

Matsuno K, Sawada J, Sugimoto M, Ogo N, Asai A. Matsuno K, et al. Among authors: asai a. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1058-61. doi: 10.1016/j.bmcl.2009.01.018. Epub 2009 Jan 11. Bioorg Med Chem Lett. 2009. PMID: 19167222

4

Identification of a small-molecule inhibitor of the interaction between Survivin and Smac/DIABLO.

Oikawa T, Unno Y, Matsuno K, Sawada J, Ogo N, Tanaka K, Asai A. Oikawa T, et al. Among authors: asai a. Biochem Biophys Res Commun. 2010 Mar 5;393(2):253-8. doi: 10.1016/j.bbrc.2010.01.113. Epub 2010 Feb 1. Biochem Biophys Res Commun. 2010. PMID: 20117083

5

Biochemical analysis of cellular target of S-trityl-L-cysteine derivatives using affinity matrix.

Shimizu M, Ishii H, Ogo N, Matsuno K, Asai A. Shimizu M, et al. Among authors: asai a. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1578-80. doi: 10.1016/j.bmcl.2010.01.088. Epub 2010 Jan 21. Bioorg Med Chem Lett. 2010. PMID: 20138511

6

S-trityl-L-cysteine derivative induces caspase-independent cell death in K562 human chronic myeloid leukemia cell line.

Shimizu M, Ishii H, Ogo N, Unno Y, Matsuno K, Sawada J, Akiyama Y, Asai A. Shimizu M, et al. Among authors: asai a. Cancer Lett. 2010 Dec 1;298(1):99-106. doi: 10.1016/j.canlet.2010.06.007. Cancer Lett. 2010. PMID: 20619960

7

Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation.

Ashizawa T, Miyata H, Ishii H, Oshita C, Matsuno K, Masuda Y, Furuya T, Okawara T, Otsuka M, Ogo N, Asai A, Akiyama Y. Ashizawa T, et al. Among authors: asai a. Int J Oncol. 2011 May;38(5):1245-52. doi: 10.3892/ijo.2011.957. Epub 2011 Feb 28. Int J Oncol. 2011. PMID: 21369699

8

Identification of novel kynurenine production-inhibiting benzenesulfonamide derivatives in cancer cells.

Nakano S, Takai K, Isaka Y, Takahashi S, Unno Y, Ogo N, Matsuno K, Takikawa O, Asai A. Nakano S, et al. Among authors: asai a. Biochem Biophys Res Commun. 2012 Mar 16;419(3):556-61. doi: 10.1016/j.bbrc.2012.02.059. Epub 2012 Feb 17. Biochem Biophys Res Commun. 2012. PMID: 22369947

9

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma.

Ashizawa T, Miyata H, Iizuka A, Komiyama M, Oshita C, Kume A, Nogami M, Yagoto M, Ito I, Oishi T, Watanabe R, Mitsuya K, Matsuno K, Furuya T, Okawara T, Otsuka M, Ogo N, Asai A, Nakasu Y, Yamaguchi K, Akiyama Y. Ashizawa T, et al. Among authors: asai a. Int J Oncol. 2013 Jul;43(1):219-27. doi: 10.3892/ijo.2013.1916. Epub 2013 Apr 23. Int J Oncol. 2013. PMID: 23612755

10

Novel multiplexed assay for identifying SH2 domain antagonists of STAT family proteins.

Takakuma K, Ogo N, Uehara Y, Takahashi S, Miyoshi N, Asai A. Takakuma K, et al. Among authors: asai a. PLoS One. 2013 Aug 16;8(8):e71646. doi: 10.1371/journal.pone.0071646. eCollection 2013. PLoS One. 2013. PMID: 23977103 Free PMC article.

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