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Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models.
Huang HY, Liao HY, Chen X, Wang SW, Cheng CW, Shahed-Al-Mahmud M, Liu YM, Mohapatra A, Chen TH, Lo JM, Wu YM, Ma HH, Chang YH, Tsai HY, Chou YC, Hsueh YP, Tsai CY, Huang PY, Chang SY, Chao TL, Kao HC, Tsai YM, Chen YH, Wu CY, Jan JT, Cheng TR, Lin KI, Ma C, Wong CH. Huang HY, et al. Among authors: jan jt. Sci Transl Med. 2022 Apr 6;14(639):eabm0899. doi: 10.1126/scitranslmed.abm0899. Epub 2022 Apr 6. Sci Transl Med. 2022. PMID: 35230146 Free PMC article.
Small molecules targeting severe acute respiratory syndrome human coronavirus.
Wu CY, Jan JT, Ma SH, Kuo CJ, Juan HF, Cheng YS, Hsu HH, Huang HC, Wu D, Brik A, Liang FS, Liu RS, Fang JM, Chen ST, Liang PH, Wong CH. Wu CY, et al. Among authors: jan jt. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):10012-7. doi: 10.1073/pnas.0403596101. Epub 2004 Jun 28. Proc Natl Acad Sci U S A. 2004. PMID: 15226499 Free PMC article.
Glycans on influenza hemagglutinin affect receptor binding and immune response.
Wang CC, Chen JR, Tseng YC, Hsu CH, Hung YF, Chen SW, Chen CM, Khoo KH, Cheng TJ, Cheng YS, Jan JT, Wu CY, Ma C, Wong CH. Wang CC, et al. Among authors: jan jt. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18137-42. doi: 10.1073/pnas.0909696106. Epub 2009 Oct 12. Proc Natl Acad Sci U S A. 2009. PMID: 19822741 Free PMC article.
Development of oseltamivir phosphonate congeners as anti-influenza agents.
Cheng TJ, Weinheimer S, Tarbet EB, Jan JT, Cheng YS, Shie JJ, Chen CL, Chen CA, Hsieh WC, Huang PW, Lin WH, Wang SY, Fang JM, Hu OY, Wong CH. Cheng TJ, et al. Among authors: jan jt. J Med Chem. 2012 Oct 25;55(20):8657-70. doi: 10.1021/jm3008486. Epub 2012 Oct 12. J Med Chem. 2012. PMID: 23009169 Free PMC article.
75 results