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Page 1
In Vivo Gene Editing in Lipid and Atherosclerosis Research.
De Giorgi M, Jarrett KE, de Aguiar Vallim TQ, Lagor WR. De Giorgi M, et al. Among authors: de aguiar vallim tq. Methods Mol Biol. 2022;2419:673-713. doi: 10.1007/978-1-0716-1924-7_42. Methods Mol Biol. 2022. PMID: 35237996
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption.
Clifford BL, Sedgeman LR, Williams KJ, Morand P, Cheng A, Jarrett KE, Chan AP, Brearley-Sholto MC, Wahlström A, Ashby JW, Barshop W, Wohlschlegel J, Calkin AC, Liu Y, Thorell A, Meikle PJ, Drew BG, Mack JJ, Marschall HU, Tarling EJ, Edwards PA, de Aguiar Vallim TQ. Clifford BL, et al. Among authors: de aguiar vallim tq. Cell Metab. 2021 Aug 3;33(8):1671-1684.e4. doi: 10.1016/j.cmet.2021.06.012. Epub 2021 Jul 15. Cell Metab. 2021. PMID: 34270928 Free PMC article.
Intestinal Deletion of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Promotes Expansion of the Resident Stem Cell Compartment.
Doerfler AM, Han J, Jarrett KE, Tang L, Jain A, Saltzman A, De Giorgi M, Chuecos M, Hurley AE, Li A, Morand P, Ayala C, Goodlett DR, Malovannaya A, Martin JF, de Aguiar Vallim TQ, Shroyer N, Lagor WR. Doerfler AM, et al. Among authors: de aguiar vallim tq. Arterioscler Thromb Vasc Biol. 2022 Apr;42(4):381-394. doi: 10.1161/ATVBAHA.122.317320. Epub 2022 Feb 17. Arterioscler Thromb Vasc Biol. 2022. PMID: 35172604 Free PMC article.
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis.
Xiao X, Kennelly JP, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P. Xiao X, et al. Among authors: de aguiar vallim tq. Nat Metab. 2023 Jan;5(1):165-181. doi: 10.1038/s42255-022-00722-6. Epub 2023 Jan 16. Nat Metab. 2023. PMID: 36646756 Free PMC article.
RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels.
Clifford BL, Jarrett KE, Cheng J, Cheng A, Seldin M, Morand P, Lee R, Chen M, Baldan A, de Aguiar Vallim TQ, Tarling EJ. Clifford BL, et al. Among authors: de aguiar vallim tq. Circ Res. 2023 Mar 31;132(7):849-863. doi: 10.1161/CIRCRESAHA.122.321938. Epub 2023 Mar 6. Circ Res. 2023. PMID: 36876496 Free PMC article.
ZFP36-mediated mRNA decay regulates metabolism.
Cicchetto AC, Jacobson EC, Sunshine H, Wilde BR, Krall AS, Jarrett KE, Sedgeman L, Turner M, Plath K, Iruela-Arispe ML, de Aguiar Vallim TQ, Christofk HR. Cicchetto AC, et al. Among authors: de aguiar vallim tq. Cell Rep. 2023 May 30;42(5):112411. doi: 10.1016/j.celrep.2023.112411. Epub 2023 Apr 21. Cell Rep. 2023. PMID: 37086408 Free PMC article.
MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice.
Cheng J, Cheng A, Clifford BL, Wu X, Hedin U, Maegdefessel L, Pamir N, Sallam T, Tarling EJ, de Aguiar Vallim TQ. Cheng J, et al. Among authors: de aguiar vallim tq. Arterioscler Thromb Vasc Biol. 2020 Feb;40(2):412-425. doi: 10.1161/ATVBAHA.119.313633. Epub 2019 Dec 19. Arterioscler Thromb Vasc Biol. 2020. PMID: 31852219 Free PMC article.
Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism.
von Scheidt M, Zhao Y, de Aguiar Vallim TQ, Che N, Wierer M, Seldin MM, Franzén O, Kurt Z, Pang S, Bongiovanni D, Yamamoto M, Edwards PA, Ruusalepp A, Kovacic JC, Mann M, Björkegren JLM, Lusis AJ, Yang X, Schunkert H. von Scheidt M, et al. Among authors: de aguiar vallim tq. Circulation. 2021 May 4;143(18):1809-1823. doi: 10.1161/CIRCULATIONAHA.120.050186. Epub 2021 Feb 25. Circulation. 2021. PMID: 33626882 Free PMC article.
36 results