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Long noncoding RNA FLRL2 alleviated nonalcoholic fatty liver disease through Arntl-Sirt1 pathway.
Chen Y, Chen X, Gao J, Xu C, Xu P, Li Y, Zhu Y, Yu C. Chen Y, et al. Among authors: gao j. FASEB J. 2019 Oct;33(10):11411-11419. doi: 10.1096/fj.201900643RRR. Epub 2019 Jul 16. FASEB J. 2019. PMID: 31311301
In NAFLD mice, FLRL2 enhancement alleviated steatosis, activated the Arntl-Sirt1 axis, and inhibited lipogenesis, ER stress, and inflammation, providing preliminary evidence of the benefits of FLRL2-mediated gene therapy in NAFLD.-Chen, Y., Chen, X., Gao, J., Xu, C. …
In NAFLD mice, FLRL2 enhancement alleviated steatosis, activated the Arntl-Sirt1 axis, and inhibited lipogenesis, ER stress, and inflammatio …
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