Yue P - Search Results

1

SS-4 is a highly selective small molecule inhibitor of STAT3 tyrosine phosphorylation that potently inhibits GBM tumorigenesis in vitro and in vivo.

Wang Y, Yang C, Sims MM, Sacher JR, Raje M, Deokar H, Yue P, Turkson J, Buolamwini JK, Pfeffer LM. Wang Y, et al. Among authors: yue p. Cancer Lett. 2022 May 1;533:215614. doi: 10.1016/j.canlet.2022.215614. Epub 2022 Mar 1. Cancer Lett. 2022. PMID: 35245627

2

Targeting STAT3 in cancer: how successful are we?

Yue P, Turkson J. Yue P, et al. Expert Opin Investig Drugs. 2009 Jan;18(1):45-56. doi: 10.1517/13543780802565791. Expert Opin Investig Drugs. 2009. PMID: 19053881 Free PMC article. Review.

3

Disruption of transcriptionally active Stat3 dimers with non-phosphorylated, salicylic acid-based small molecules: potent in vitro and tumor cell activities.

Fletcher S, Singh J, Zhang X, Yue P, Page BD, Sharmeen S, Shahani VM, Zhao W, Schimmer AD, Turkson J, Gunning PT. Fletcher S, et al. Among authors: yue p. Chembiochem. 2009 Aug 17;10(12):1959-64. doi: 10.1002/cbic.200900172. Chembiochem. 2009. PMID: 19644994 Free PMC article. No abstract available.

4

A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.

Zhang X, Yue P, Fletcher S, Zhao W, Gunning PT, Turkson J. Zhang X, et al. Among authors: yue p. Biochem Pharmacol. 2010 May 15;79(10):1398-409. doi: 10.1016/j.bcp.2010.01.001. Epub 2010 Jan 11. Biochem Pharmacol. 2010. PMID: 20067773 Free PMC article.

5

Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.

Jaganathan S, Yue P, Turkson J. Jaganathan S, et al. Among authors: yue p. J Pharmacol Exp Ther. 2010 May;333(2):373-81. doi: 10.1124/jpet.109.162669. Epub 2010 Jan 25. J Pharmacol Exp Ther. 2010. PMID: 20100905 Free PMC article.

6

Coordination complex SH2 domain proteomimetics: an alternative approach to disrupting oncogenic protein-protein interactions.

Drewry JA, Fletcher S, Yue P, Marushchak D, Zhao W, Sharmeen S, Zhang X, Schimmer AD, Gradinaru C, Turkson J, Gunning PT. Drewry JA, et al. Among authors: yue p. Chem Commun (Camb). 2010 Feb 14;46(6):892-4. doi: 10.1039/b919608k. Epub 2009 Dec 1. Chem Commun (Camb). 2010. PMID: 20107641 Free PMC article.

7

Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein.

Shahani VM, Yue P, Fletcher S, Sharmeen S, Sukhai MA, Luu DP, Zhang X, Sun H, Zhao W, Schimmer AD, Turkson J, Gunning PT. Shahani VM, et al. Among authors: yue p. Bioorg Med Chem. 2011 Mar 1;19(5):1823-38. doi: 10.1016/j.bmc.2010.12.010. Epub 2010 Dec 9. Bioorg Med Chem. 2011. PMID: 21216604 Free PMC article.

8

Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies.

Shahani VM, Yue P, Haftchenary S, Zhao W, Lukkarila JL, Zhang X, Ball D, Nona C, Gunning PT, Turkson J. Shahani VM, et al. Among authors: yue p. ACS Med Chem Lett. 2011 Jan 13;2(1):79-84. doi: 10.1021/ml100224d. Epub 2010 Oct 25. ACS Med Chem Lett. 2011. Retraction in: ACS Med Chem Lett. 2023 Sep 19;14(10):1482. doi: 10.1021/acsmedchemlett.3c00405 PMID: 21243039 Free PMC article. Retracted.

9

A functional nuclear epidermal growth factor receptor, SRC and Stat3 heteromeric complex in pancreatic cancer cells.

Jaganathan S, Yue P, Paladino DC, Bogdanovic J, Huo Q, Turkson J. Jaganathan S, et al. Among authors: yue p. PLoS One. 2011 May 5;6(5):e19605. doi: 10.1371/journal.pone.0019605. PLoS One. 2011. Retraction in: PLoS One. 2019 Feb 20;14(2):e0212884. doi: 10.1371/journal.pone.0212884 PMID: 21573184 Free PMC article. Retracted.

10

Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.

Fletcher S, Page BD, Zhang X, Yue P, Li ZH, Sharmeen S, Singh J, Zhao W, Schimmer AD, Trudel S, Turkson J, Gunning PT. Fletcher S, et al. Among authors: yue p. ChemMedChem. 2011 Aug 1;6(8):1459-70. doi: 10.1002/cmdc.201100194. Epub 2011 May 25. ChemMedChem. 2011. PMID: 21618433 Free PMC article.

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