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Novel Bruton's tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions.
Schiller H, Huth F, Schuhler C, Drollmann A, Kaul M, Woessner R, Shah B, Weis W, End P. Schiller H, et al. Among authors: end p. Eur J Pharm Sci. 2022 May 1;172:106155. doi: 10.1016/j.ejps.2022.106155. Epub 2022 Mar 3. Eur J Pharm Sci. 2022. PMID: 35247543 Free article.
Absorption, Distribution, Metabolism, and Excretion of the Oral Prostaglandin D2 Receptor 2 Antagonist Fevipiprant (QAW039) in Healthy Volunteers and In Vitro.
Pearson D, Weiss HM, Jin Y, Jaap van Lier J, Erpenbeck VJ, Glaenzel U, End P, Woessner R, Eggimann F, Camenisch G. Pearson D, et al. Among authors: end p. Drug Metab Dispos. 2017 Jul;45(7):817-825. doi: 10.1124/dmd.117.075358. Epub 2017 Apr 25. Drug Metab Dispos. 2017. PMID: 28442499 Clinical Trial.
Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial.
Risitano AM, Röth A, Soret J, Frieri C, de Fontbrune FS, Marano L, Alashkar F, Benajiba L, Marotta S, Rozenberg I, Milojevic J, End P, Nidamarthy PK, Junge G, Peffault de Latour R. Risitano AM, et al. Among authors: end p. Lancet Haematol. 2021 May;8(5):e344-e354. doi: 10.1016/S2352-3026(21)00028-4. Epub 2021 Mar 23. Lancet Haematol. 2021. PMID: 33765419 Clinical Trial.
20 results