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CDK7/12/13 inhibition targets an oscillating leukemia stem cell network and synergizes with venetoclax in acute myeloid leukemia.
He L, Arnold C, Thoma J, Rohde C, Kholmatov M, Garg S, Hsiao CC, Viol L, Zhang K, Sun R, Schmidt C, Janssen M, MacRae T, Huber K, Thiede C, Hébert J, Sauvageau G, Spratte J, Fluhr H, Aust G, Müller-Tidow C, Niehrs C, Pereira G, Hamann J, Tanaka M, Zaugg JB, Pabst C. He L, et al. Among authors: zhang k. EMBO Mol Med. 2022 Apr 7;14(4):e14990. doi: 10.15252/emmm.202114990. Epub 2022 Mar 7. EMBO Mol Med. 2022. PMID: 35253392 Free PMC article.
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex.
Da Silva F, Zhang K, Pinson A, Fatti E, Wilsch-Bräuninger M, Herbst J, Vidal V, Schedl A, Huttner WB, Niehrs C. Da Silva F, et al. Among authors: zhang k. EMBO J. 2021 Oct 1;40(19):e108041. doi: 10.15252/embj.2021108041. Epub 2021 Aug 25. EMBO J. 2021. PMID: 34431536 Free PMC article.
Mucociliary Wnt signaling promotes cilia biogenesis and beating.
Seidl C, Da Silva F, Zhang K, Wohlgemuth K, Omran H, Niehrs C. Seidl C, et al. Among authors: zhang k. Nat Commun. 2023 Mar 6;14(1):1259. doi: 10.1038/s41467-023-36743-2. Nat Commun. 2023. PMID: 36878953 Free PMC article.
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