Smith MD - Search Results

1

Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses.

Chen LL, Morcelle C, Cheng ZL, Chen X, Xu Y, Gao Y, Song J, Li Z, Smith MD, Shi M, Zhu Y, Zhou N, Cheng M, He C, Liu KY, Lu G, Zhang L, Zhang C, Zhang J, Sun Y, Qi T, Lyu Y, Ren ZZ, Tan XM, Yin J, Lan F, Liu Y, Yang H, Qian M, Duan C, Chang X, Zhou Y, Shen L, Baldwin AS, Guan KL, Xiong Y, Ye D. Chen LL, et al. Among authors: smith md. Nat Cell Biol. 2022 Mar;24(3):353-363. doi: 10.1038/s41556-022-00853-8. Epub 2022 Mar 7. Nat Cell Biol. 2022. PMID: 35256775 Free PMC article.

2

p18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors.

Bai F, Pei XH, Nishikawa T, Smith MD, Xiong Y. Bai F, et al. Among authors: smith md. Mol Cell Biol. 2007 Feb;27(4):1495-504. doi: 10.1128/MCB.01764-06. Epub 2006 Dec 4. Mol Cell Biol. 2007. PMID: 17145768 Free PMC article.

3

p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers.

Pei XH, Bai F, Smith MD, Xiong Y. Pei XH, et al. Among authors: smith md. Cancer Res. 2007 Apr 1;67(7):3162-70. doi: 10.1158/0008-5472.CAN-06-4517. Cancer Res. 2007. PMID: 17409423

4

CDK inhibitor p18(INK4c) is a downstream target of GATA3 and restrains mammary luminal progenitor cell proliferation and tumorigenesis.

Pei XH, Bai F, Smith MD, Usary J, Fan C, Pai SY, Ho IC, Perou CM, Xiong Y. Pei XH, et al. Among authors: smith md. Cancer Cell. 2009 May 5;15(5):389-401. doi: 10.1016/j.ccr.2009.03.004. Cancer Cell. 2009. PMID: 19411068 Free PMC article.

5

p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb.

Zeng Y, Kotake Y, Pei XH, Smith MD, Xiong Y. Zeng Y, et al. Among authors: smith md. Cancer Res. 2011 Apr 1;71(7):2781-92. doi: 10.1158/0008-5472.CAN-10-3483. Epub 2011 Mar 29. Cancer Res. 2011. PMID: 21447739 Free PMC article.

6

Cytoplasmic CUL9/PARC ubiquitin ligase is a tumor suppressor and promotes p53-dependent apoptosis.

Pei XH, Bai F, Li Z, Smith MD, Whitewolf G, Jin R, Xiong Y. Pei XH, et al. Among authors: smith md. Cancer Res. 2011 Apr 15;71(8):2969-77. doi: 10.1158/0008-5472.CAN-10-4300. Epub 2011 Apr 12. Cancer Res. 2011. PMID: 21487039 Free PMC article.

7

A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.

Zha Z, Han X, Smith MD, Liu Y, Giguère PM, Kopanja D, Raychaudhuri P, Siderovski DP, Guan KL, Lei QY, Xiong Y. Zha Z, et al. Among authors: smith md. Mol Cell. 2015 Jun 4;58(5):794-803. doi: 10.1016/j.molcel.2015.04.017. Epub 2015 May 14. Mol Cell. 2015. PMID: 25982117 Free PMC article.

8

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.

Groh BS, Yan F, Smith MD, Yu Y, Chen X, Xiong Y. Groh BS, et al. Among authors: smith md. EMBO Rep. 2016 May;17(5):638-47. doi: 10.15252/embr.201540500. Epub 2016 Apr 9. EMBO Rep. 2016. PMID: 27113764 Free PMC article.

9

Hypertension-associated C825T polymorphism impairs the function of Gβ3 to target GRK2 ubiquitination.

Zha Z, Han XR, Smith MD, Lei QY, Guan KL, Xiong Y. Zha Z, et al. Among authors: smith md. Cell Discov. 2016 Apr 26;2:16005. doi: 10.1038/celldisc.2016.5. eCollection 2016. Cell Discov. 2016. PMID: 27462452 Free PMC article.

10

Tumor suppressor TET2 promotes cancer immunity and immunotherapy efficacy.

Xu YP, Lv L, Liu Y, Smith MD, Li WC, Tan XM, Cheng M, Li Z, Bovino M, Aubé J, Xiong Y. Xu YP, et al. Among authors: smith md. J Clin Invest. 2019 Jul 16;129(10):4316-4331. doi: 10.1172/JCI129317. J Clin Invest. 2019. PMID: 31310587 Free PMC article.

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