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Chronic Lymphocytic Leukemia-Derived IL-10 Suppresses Antitumor Immunity.
Alhakeem SS, McKenna MK, Oben KZ, Noothi SK, Rivas JR, Hildebrandt GC, Fleischman RA, Rangnekar VM, Muthusamy N, Bondada S. Alhakeem SS, et al. Among authors: mckenna mk. J Immunol. 2018 Jun 15;200(12):4180-4189. doi: 10.4049/jimmunol.1800241. Epub 2018 Apr 30. J Immunol. 2018. PMID: 29712773 Free PMC article.
Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A.
Oben KZ, Alhakeem SS, McKenna MK, Brandon JA, Mani R, Noothi SK, Jinpeng L, Akunuru S, Dhar SK, Singh IP, Liang Y, Wang C, Abdel-Latif A, Stills HF Jr, St Clair DK, Geiger H, Muthusamy N, Tohyama K, Gupta RC, Bondada S. Oben KZ, et al. Among authors: mckenna mk. Oncotarget. 2017 Aug 24;8(44):77436-77452. doi: 10.18632/oncotarget.20497. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100399 Free PMC article.
Anti-cancer activity of withaferin A in B-cell lymphoma.
McKenna MK, Gachuki BW, Alhakeem SS, Oben KN, Rangnekar VM, Gupta RC, Bondada S. McKenna MK, et al. Cancer Biol Ther. 2015;16(7):1088-98. doi: 10.1080/15384047.2015.1046651. Cancer Biol Ther. 2015. PMID: 26020511 Free PMC article.
Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia.
Ataca Atilla P, McKenna MK, Tashiro H, Srinivasan M, Mo F, Watanabe N, Simons BW, McLean Stevens A, Redell MS, Heslop HE, Mamonkin M, Brenner MK, Atilla E. Ataca Atilla P, et al. Among authors: mckenna mk. J Immunother Cancer. 2020 Sep;8(2):e001229. doi: 10.1136/jitc-2020-001229. J Immunother Cancer. 2020. PMID: 32938629 Free PMC article.
35 results