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Page 1
High Viral Specific Antibody Convalescent Plasma Effectively Neutralizes SARS-CoV-2 Variants of Concern.
Li M, Beck EJ, Laeyendecker O, Eby Y, Tobian AA, Caturegli P, Wouters C, Chiklis GR, Block W, McKie R, Joyner M, Wiltshire TD, Dietz AB, Gniadek TJ, Shapiro A, Yarava A, Lane K, Hanley D, Bloch EM, Shoham S, Cachay ER, Meisenberg BR, Huaman MA, Fukuta Y, Patel B, Heath SL, Levine AC, Paxton JH, Anjan S, Gerber JM, Gebo KA, Casadevall A, Pekosz A, Sullivan DJ; CSSC group. Li M, et al. Among authors: hanley d. medRxiv [Preprint]. 2022 Mar 2:2022.03.01.22271662. doi: 10.1101/2022.03.01.22271662. medRxiv. 2022. Update in: Blood Adv. 2022 Jun 28;6(12):3678-3683. doi: 10.1182/bloodadvances.2022007410 PMID: 35262085 Free PMC article. Updated. Preprint.
Randomized controlled trial transfusing convalescent plasma as post-exposure prophylaxis against SARS-CoV-2 infection.
Shoham S, Bloch EM, Casadevall A, Hanley D, Lau B, Gebo K, Cachay E, Kassaye SG, Paxton JH, Gerber J, Levine AC, Currier J, Patel B, Allen ES, Anjan S, Appel L, Baksh S, Blair PW, Bowen A, Broderick P, Caputo CA, Cluzet V, Cordisco ME, Cruser D, Ehrhardt S, Forthal D, Fukuta Y, Gawad AL, Gniadek T, Hammel J, Huaman MA, Jabs DA, Jedlicka A, Karlen N, Klein S, Laeyendecker O, Lane K, McBee N, Meisenberg B, Merlo C, Mosnaim G, Park HS, Pekosz A, Petrini J, Rausch W, Shade DM, Shapiro JR, Singleton JR, Sutcliffe C, Thomas DL, Yarava A, Zand M, Zenilman JM, Tobian AAR, Sullivan D. Shoham S, et al. Among authors: hanley d. medRxiv [Preprint]. 2021 Dec 14:2021.12.13.21267611. doi: 10.1101/2021.12.13.21267611. medRxiv. 2021. Update in: Clin Infect Dis. 2023 Feb 8;76(3):e477-e486. doi: 10.1093/cid/ciac372 PMID: 34931202 Free PMC article. Updated. Preprint.
Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma.
Sullivan DJ, Gebo KA, Shoham S, Bloch EM, Lau B, Shenoy AG, Mosnaim GS, Gniadek TJ, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Gerber JM, Petrini JR, Broderick PB, Rausch W, Cordisco ME, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Raval JS, Kassaye SG, Foster EC, Roth M, Marshall CE, Yarava A, Lane K, McBee NA, Gawad AL, Karlen N, Singh A, Ford DE, Jabs DA, Appel LJ, Shade DM, Ehrhardt S, Baksh SN, Laeyendecker O, Pekosz A, Klein SL, Casadevall A, Tobian AAR, Hanley DF. Sullivan DJ, et al. Among authors: hanley df. medRxiv [Preprint]. 2021 Dec 21:2021.12.10.21267485. doi: 10.1101/2021.12.10.21267485. medRxiv. 2021. PMID: 34981068 Free PMC article. Preprint.
COVID-19 Convalescent Plasma Outpatient Therapy to Prevent Outpatient Hospitalization: A Meta-analysis of Individual Participant Data From Five Randomized Trials.
Levine AC, Fukuta Y, Huaman MA, Ou J, Meisenberg BR, Patel B, Paxton JH, Hanley DF, Rijnders BJ, Gharbharan A, Rokx C, Zwaginga JJ, Alemany A, Mitjà O, Ouchi D, Millat-Martinez P, Durkalski-Mauldin V, Korley FK, Dumont LJ, Callaway CW, Libster R, Marc GP, Wappner D, Esteban I, Polack F, Sullivan DJ. Levine AC, et al. Among authors: hanley df. medRxiv [Preprint]. 2022 Dec 18:2022.12.16.22283585. doi: 10.1101/2022.12.16.22283585. medRxiv. 2022. Update in: Clin Infect Dis. 2023 Jun 16;76(12):2077-2086. doi: 10.1093/cid/ciad088 PMID: 36561181 Free PMC article. Updated. Preprint.
Early Treatment, Inflammation and Post-COVID Conditions.
Gebo KA, Heath SL, Fukuta Y, Zhu X, Baksh S, Abraham AG, Habtehyimer F, Shade D, Ruff J, Ram M, Laeyendecker O, Fernandez RE, Patel EU, Baker OR, Shoham S, Cachay ER, Currier JS, Gerber JM, Meisenberg B, Forthal DN, Hammitt LL, Huaman MA, Levine A, Mosnaim GS, Patel B, Paxton JH, Raval JS, Sutcliffe CG, Anjan S, Gniadek T, Kassaye S, Blair JE, Lane K, McBee NA, Gawad AL, Das P, Klein SL, Pekosz A, Casadevall A, Bloch EM, Hanley D, Tobian AAR, Sullivan DJ. Gebo KA, et al. Among authors: hanley d. medRxiv [Preprint]. 2023 Feb 16:2023.02.13.23285855. doi: 10.1101/2023.02.13.23285855. medRxiv. 2023. PMID: 36824860 Free PMC article. Preprint.
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial.
Park HS, Yin A, Barranta C, Lee JS, Caputo CA, Sachithanandham J, Li M, Yoon S, Sitaras I, Jedlicka A, Eby Y, Ram M, Fernandez RE, Baker OR, Shenoy AG, Mosnaim GS, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Gerber JM, Petrini JR, Broderick PB, Rausch W, Cordisco ME, Hammel J, Greenblatt B, Cluzet VC, Cruser D, Oei K, Abinante M, Hammitt LL, Sutcliffe CG, Forthal DN, Zand MS, Cachay ER, Raval JS, Kassaye SG, Marshall CE, Yarava A, Lane K, McBee NA, Gawad AL, Karlen N, Singh A, Ford DE, Jabs DA, Appel LJ, Shade DM, Lau B, Ehrhardt S, Baksh SN, Shapiro JR, Ou J, Na YB, Knoll MD, Ornelas-Gatdula E, Arroyo-Curras N, Gniadek TJ, Caturegli P, Wu J, Ndahiro N, Betenbaugh MJ, Ziman A, Hanley DF, Casadevall A, Shoham S, Bloch EM, Gebo KA, Tobian AA, Laeyendecker O, Pekosz A, Klein SL, Sullivan DJ. Park HS, et al. Among authors: hanley df. JCI Insight. 2024 Mar 14;9(8):e178460. doi: 10.1172/jci.insight.178460. JCI Insight. 2024. PMID: 38483534 Free PMC article. Clinical Trial.
Estimates of actual and potential lives saved in the United States from the use of COVID-19 convalescent plasma.
Dragotakes Q, Johnson PW, Buras MR, Carter RE, Joyner MJ, Bloch E, Gebo KA, Hanley DF, Henderson JP, Pirofski LA, Shoham S, Senefeld JW, Tobian AAR, Wiggins CC, Wright RS, Paneth NS, Sullivan DJ, Casadevall A. Dragotakes Q, et al. Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2414957121. doi: 10.1073/pnas.2414957121. Epub 2024 Oct 1. Proc Natl Acad Sci U S A. 2024. PMID: 39352932 Free PMC article.
Hydroxychloroquine/chloroquine for the treatment of hospitalized patients with COVID-19: An individual participant data meta-analysis.
Di Stefano L, Ogburn EL, Ram M, Scharfstein DO, Li T, Khanal P, Baksh SN, McBee N, Gruber J, Gildea MR, Clark MR, Goldenberg NA, Bennani Y, Brown SM, Buckel WR, Clement ME, Mulligan MJ, O'Halloran JA, Rauseo AM, Self WH, Semler MW, Seto T, Stout JE, Ulrich RJ, Victory J, Bierer BE, Hanley DF, Freilich D. Di Stefano L, et al. Among authors: hanley df. medRxiv [Preprint]. 2022 Aug 16:2022.01.10.22269008. doi: 10.1101/2022.01.10.22269008. medRxiv. 2022. Update in: PLoS One. 2022 Sep 29;17(9):e0273526. doi: 10.1371/journal.pone.0273526 PMID: 35043124 Free PMC article. Updated. Preprint.
Selecting trial centers using a standardized, automated site assessment survey instrument (SASI).
Lane K, Hillery S, Majkowski R, Barney BJ, Amirault D, Nelson SJ, Bailey M, Unsicker EH, Stroud M, Eyzaguirre LM, Gawad A, Nanni A, Mirzoyan G, Cohen T, Waddy SP, Wiley K, Harris PA, Ford DE, Hanley D; Trial Innovation Network. Lane K, et al. Among authors: hanley d. Contemp Clin Trials. 2024 Aug;143:107583. doi: 10.1016/j.cct.2024.107583. Epub 2024 May 29. Contemp Clin Trials. 2024. PMID: 38821259
Valproic acid use is associated with diminished risk of contracting COVID-19, and diminished disease severity: Epidemiologic and in vitro analysis reveal mechanistic insights.
Watson A, Shah P, Lee D, Liang S, Joshi G, Metitiri E, Chowdhury WH, Bacich D, Dube P, Xiang Y, Hanley D, Martinez-Sobrido L, Rodriguez R. Watson A, et al. Among authors: hanley d. PLoS One. 2024 Aug 2;19(8):e0307154. doi: 10.1371/journal.pone.0307154. eCollection 2024. PLoS One. 2024. PMID: 39093886 Free PMC article.
893 results