Rosenthal PJ - Search Results

1

Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues.

Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF. Brinkmann S, et al. Among authors: rosenthal pj. ACS Chem Biol. 2022 Mar 18;17(3):576-589. doi: 10.1021/acschembio.1c00861. Epub 2022 Mar 9. ACS Chem Biol. 2022. PMID: 35262340

2

Stage-specific antimalarial activity of cysteine protease inhibitors.

Shenai BR, Semenov AV, Rosenthal PJ. Shenai BR, et al. Among authors: rosenthal pj. Biol Chem. 2002 May;383(5):843-7. doi: 10.1515/BC.2002.089. Biol Chem. 2002. PMID: 12108550

3

Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.

Na BK, Shenai BR, Sijwali PS, Choe Y, Pandey KC, Singh A, Craik CS, Rosenthal PJ. Na BK, et al. Among authors: rosenthal pj. Biochem J. 2004 Mar 1;378(Pt 2):529-38. doi: 10.1042/BJ20031487. Biochem J. 2004. PMID: 14629194 Free PMC article.

4

Antimalarial activities of novel synthetic cysteine protease inhibitors.

Lee BJ, Singh A, Chiang P, Kemp SJ, Goldman EA, Weinhouse MI, Vlasuk GP, Rosenthal PJ. Lee BJ, et al. Among authors: rosenthal pj. Antimicrob Agents Chemother. 2003 Dec;47(12):3810-4. doi: 10.1128/AAC.47.12.3810-3814.2003. Antimicrob Agents Chemother. 2003. PMID: 14638488 Free PMC article.

5

Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites.

Sijwali PS, Kato K, Seydel KB, Gut J, Lehman J, Klemba M, Goldberg DE, Miller LH, Rosenthal PJ. Sijwali PS, et al. Among authors: rosenthal pj. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8721-6. doi: 10.1073/pnas.0402738101. Epub 2004 May 27. Proc Natl Acad Sci U S A. 2004. PMID: 15166288 Free PMC article.

6

Selection of cysteine protease inhibitor-resistant malaria parasites is accompanied by amplification of falcipain genes and alteration in inhibitor transport.

Singh A, Rosenthal PJ. Singh A, et al. Among authors: rosenthal pj. J Biol Chem. 2004 Aug 20;279(34):35236-41. doi: 10.1074/jbc.M404235200. Epub 2004 Jun 10. J Biol Chem. 2004. PMID: 15192087 Free article.

7

The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif.

Pandey KC, Wang SX, Sijwali PS, Lau AL, McKerrow JH, Rosenthal PJ. Pandey KC, et al. Among authors: rosenthal pj. Proc Natl Acad Sci U S A. 2005 Jun 28;102(26):9138-43. doi: 10.1073/pnas.0502368102. Epub 2005 Jun 17. Proc Natl Acad Sci U S A. 2005. PMID: 15964982 Free PMC article.

8

Plasmodium falciparum: biochemical characterization of the cysteine protease falcipain-2'.

Singh N, Sijwali PS, Pandey KC, Rosenthal PJ. Singh N, et al. Among authors: rosenthal pj. Exp Parasitol. 2006 Mar;112(3):187-92. doi: 10.1016/j.exppara.2005.10.007. Epub 2005 Dec 7. Exp Parasitol. 2006. PMID: 16337629

9

Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion.

Pandey KC, Singh N, Arastu-Kapur S, Bogyo M, Rosenthal PJ. Pandey KC, et al. Among authors: rosenthal pj. PLoS Pathog. 2006 Nov;2(11):e117. doi: 10.1371/journal.ppat.0020117. PLoS Pathog. 2006. PMID: 17083274 Free PMC article.

10

Screening of protease inhibitors as antiplasmodial agents. Part I: Aziridines and epoxides.

Schulz F, Gelhaus C, Degel B, Vicik R, Heppner S, Breuning A, Leippe M, Gut J, Rosenthal PJ, Schirmeister T. Schulz F, et al. Among authors: rosenthal pj. ChemMedChem. 2007 Aug;2(8):1214-24. doi: 10.1002/cmdc.200700070. ChemMedChem. 2007. PMID: 17562535

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