Ungvári O - Search Results

1

Identifying Novel Inhibitors for Hepatic Organic Anion Transporting Polypeptides by Machine Learning-Based Virtual Screening.

Tuerkova A, Bongers BJ, Norinder U, Ungvári O, Székely V, Tarnovskiy A, Szakács G, Özvegy-Laczka C, van Westen GJP, Zdrazil B. Tuerkova A, et al. Among authors: ungvari o. J Chem Inf Model. 2022 Dec 26;62(24):6323-6335. doi: 10.1021/acs.jcim.1c01460. Epub 2022 Mar 11. J Chem Inf Model. 2022. PMID: 35274943 Free PMC article. Review.

2

Data-Driven Ensemble Docking to Map Molecular Interactions of Steroid Analogs with Hepatic Organic Anion Transporting Polypeptides.

Tuerkova A, Ungvári O, Laczkó-Rigó R, Mernyák E, Szakács G, Özvegy-Laczka C, Zdrazil B. Tuerkova A, et al. Among authors: ungvari o. J Chem Inf Model. 2021 Jun 28;61(6):3109-3127. doi: 10.1021/acs.jcim.1c00362. Epub 2021 Jun 9. J Chem Inf Model. 2021. PMID: 34105971 Free PMC article.

3

8-acetoxy-trisulfopyrene as the first activatable fluorogenic probe for add-and-read assessment of Organic anion-transporting polypeptides, OATP1B1, OATP1B3, and OATP2B1.

Ungvári O, Király L, Bakos É, Özvegy-Laczka C. Ungvári O, et al. FASEB J. 2021 Sep;35(9):e21863. doi: 10.1096/fj.202100648R. FASEB J. 2021. PMID: 34411334

4

Fluorescent probes for the dual investigation of MRP2 and OATP1B1 function and drug interactions.

Székely V, Patik I, Ungvári O, Telbisz Á, Szakács G, Bakos É, Özvegy-Laczka C. Székely V, et al. Among authors: ungvari o. Eur J Pharm Sci. 2020 Aug 1;151:105395. doi: 10.1016/j.ejps.2020.105395. Epub 2020 May 29. Eur J Pharm Sci. 2020. PMID: 32473861 Free article.

5

Effects of Chrysin and Its Major Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide on Cytochrome P450 Enzymes and on OATP, P-gp, BCRP, and MRP2 Transporters.

Mohos V, Fliszár-Nyúl E, Ungvári O, Bakos É, Kuffa K, Bencsik T, Zsidó BZ, Hetényi C, Telbisz Á, Özvegy-Laczka C, Poór M. Mohos V, et al. Among authors: ungvari o. Drug Metab Dispos. 2020 Oct;48(10):1064-1073. doi: 10.1124/dmd.120.000085. Epub 2020 Jul 13. Drug Metab Dispos. 2020. PMID: 32661014

6

Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters.

Mohos V, Fliszár-Nyúl E, Ungvári O, Kuffa K, Needs PW, Kroon PA, Telbisz Á, Özvegy-Laczka C, Poór M. Mohos V, et al. Among authors: ungvari o. Nutrients. 2020 Jul 31;12(8):2306. doi: 10.3390/nu12082306. Nutrients. 2020. PMID: 32751996 Free PMC article.

7

The fluorescence-based competitive counterflow assay developed for organic anion transporting polypeptides 1A2, 1B1, 1B3 and 2B1 identifies pentamidine as a selective OATP1A2 substrate.

Ungvári O, Bakos É, Kovacsics D, Özvegy-Laczka C. Ungvári O, et al. FASEB J. 2023 Nov;37(11):e23223. doi: 10.1096/fj.202300530RR. FASEB J. 2023. PMID: 37781971

8

Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-Tox.

Özvegy-Laczka C, Ungvári O, Bakos É. Özvegy-Laczka C, et al. Among authors: ungvari o. Biochem Pharmacol. 2023 Mar;209:115448. doi: 10.1016/j.bcp.2023.115448. Epub 2023 Feb 8. Biochem Pharmacol. 2023. PMID: 36758706 Free article. Review.

9

Interactions of Mycotoxin Alternariol with Cytochrome P450 Enzymes and OATP Transporters.

Fliszár-Nyúl E, Ungvári O, Dombi Á, Özvegy-Laczka C, Poór M. Fliszár-Nyúl E, et al. Among authors: ungvari o. Metabolites. 2022 Dec 28;13(1):45. doi: 10.3390/metabo13010045. Metabolites. 2022. PMID: 36676970 Free PMC article.

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