Parnell SM - Search Results

1

Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration.

Cosway EJ, White AJ, Parnell SM, Schweighoffer E, Jolin HE, Bacon A, Rodewald HR, Tybulewicz V, McKenzie ANJ, Jenkinson WE, Anderson G. Cosway EJ, et al. Among authors: parnell sm. Sci Immunol. 2022 Mar 11;7(69):eabn3286. doi: 10.1126/sciimmunol.abn3286. Epub 2022 Mar 11. Sci Immunol. 2022. PMID: 35275754 Free PMC article.

2

Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc.

Jenkinson EJ, Parnell S, Shuttleworth J, Owen JJ, Anderson G. Jenkinson EJ, et al. J Immunol. 1999 Dec 1;163(11):5781-5. J Immunol. 1999. PMID: 10570260

3

Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling.

Anderson G, Pongracz J, Parnell S, Jenkinson EJ. Anderson G, et al. Eur J Immunol. 2001 Nov;31(11):3349-54. doi: 10.1002/1521-4141(200111)31:11<3349::aid-immu3349>3.0.co;2-s. Eur J Immunol. 2001. PMID: 11745352 Free article.

4

Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes.

Pongracz J, Parnell S, Anderson G, Jaffrézou JP, Jenkinson E. Pongracz J, et al. Mol Immunol. 2003 Jun;39(16):1013-23. doi: 10.1016/s0161-5890(03)00044-0. Mol Immunol. 2003. PMID: 12749908

5

T/B lineage choice occurs prior to intrathymic Notch signaling.

Harman BC, Jenkinson WE, Parnell SM, Rossi SW, Jenkinson EJ, Anderson G. Harman BC, et al. Among authors: parnell sm. Blood. 2005 Aug 1;106(3):886-92. doi: 10.1182/blood-2004-12-4881. Epub 2005 Apr 21. Blood. 2005. PMID: 15845899 Free article.

6

Establishment and functioning of intrathymic microenvironments.

Anderson G, Jenkinson WE, Jones T, Parnell SM, Kinsella FA, White AJ, Pongrac'z JE, Rossi SW, Jenkinson EJ. Anderson G, et al. Among authors: parnell sm. Immunol Rev. 2006 Feb;209:10-27. doi: 10.1111/j.0105-2896.2006.00347.x. Immunol Rev. 2006. PMID: 16448531 Review.

7

Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development.

Pongracz JE, Parnell SM, Jones T, Anderson G, Jenkinson EJ. Pongracz JE, et al. Among authors: parnell sm. Eur J Immunol. 2006 Sep;36(9):2376-83. doi: 10.1002/eji.200535721. Eur J Immunol. 2006. PMID: 16897815 Free article.

8

Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15).

Kim MY, Toellner KM, White A, McConnell FM, Gaspal FM, Parnell SM, Jenkinson E, Anderson G, Lane PJ. Kim MY, et al. Among authors: parnell sm. J Immunol. 2006 Sep 1;177(5):3074-81. doi: 10.4049/jimmunol.177.5.3074. J Immunol. 2006. PMID: 16920944

9

PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches.

Jenkinson WE, Rossi SW, Parnell SM, Jenkinson EJ, Anderson G. Jenkinson WE, et al. Among authors: parnell sm. Blood. 2007 Feb 1;109(3):954-60. doi: 10.1182/blood-2006-05-023143. Epub 2006 Sep 28. Blood. 2007. PMID: 17008543 Free article.

10

RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.

Rossi SW, Kim MY, Leibbrandt A, Parnell SM, Jenkinson WE, Glanville SH, McConnell FM, Scott HS, Penninger JM, Jenkinson EJ, Lane PJ, Anderson G. Rossi SW, et al. Among authors: parnell sm. J Exp Med. 2007 Jun 11;204(6):1267-72. doi: 10.1084/jem.20062497. Epub 2007 May 14. J Exp Med. 2007. PMID: 17502664 Free PMC article.

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