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Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth.
He A, Tian S, Kopper O, Horan DJ, Chen P, Bronson RT, Sheng R, Wu H, Sui L, Zhou K, Tao L, Wu Q, Huang Y, Shen Z, Han S, Chen X, Chen H, He X, Robling AG, Jin R, Clevers H, Xiang D, Li Z, Dong M. He A, et al. Among authors: he x. PLoS Biol. 2023 Nov 9;21(11):e3002353. doi: 10.1371/journal.pbio.3002353. eCollection 2023 Nov. PLoS Biol. 2023. PMID: 37943878 Free PMC article.
USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase separation potential.
Wang Y, Mao A, Liu J, Li P, Zheng S, Tong T, Li Z, Zhang H, Ma L, Lin J, Pang Z, Han Q, Qi F, Zhang X, Chen M, He X, Zhang X, Fei T, Liu BF, Gao D, Cao L, Wang Q, Li Y, Sheng R. Wang Y, et al. Among authors: he x. Cell Chem Biol. 2023 Nov 16;30(11):1436-1452.e10. doi: 10.1016/j.chembiol.2023.07.016. Epub 2023 Aug 22. Cell Chem Biol. 2023. PMID: 37611590
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