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Page 1
The Pandemic Response Box─Accelerating Drug Discovery Efforts after Disease Outbreaks.
Samby K, Besson D, Dutta A, Patra B, Doy A, Glossop P, Mills J, Whitlock G, Hooft van Huijsduijnen R, Monaco A, Bilbe G, Mowbray C, Perry B, Adam A, Wells TNC, Willis PA. Samby K, et al. Among authors: mowbray c. ACS Infect Dis. 2022 Apr 8;8(4):713-720. doi: 10.1021/acsinfecdis.1c00527. Epub 2022 Mar 14. ACS Infect Dis. 2022. PMID: 35286809 Free PMC article.
Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity.
Mowbray CE, Braillard S, Speed W, Glossop PA, Whitlock GA, Gibson KR, Mills JE, Brown AD, Gardner JM, Cao Y, Hua W, Morgans GL, Feijens PB, Matheeussen A, Maes LJ. Mowbray CE, et al. J Med Chem. 2015 Dec 24;58(24):9615-24. doi: 10.1021/acs.jmedchem.5b01456. Epub 2015 Dec 4. J Med Chem. 2015. PMID: 26571076 Free article.
Recent Development of Visceral Leishmaniasis Treatments: Successes, Pitfalls, and Perspectives.
Alves F, Bilbe G, Blesson S, Goyal V, Monnerat S, Mowbray C, Muthoni Ouattara G, Pécoul B, Rijal S, Rode J, Solomos A, Strub-Wourgaft N, Wasunna M, Wells S, Zijlstra EE, Arana B, Alvar J. Alves F, et al. Among authors: mowbray c. Clin Microbiol Rev. 2018 Aug 29;31(4):e00048-18. doi: 10.1128/CMR.00048-18. Print 2018 Oct. Clin Microbiol Rev. 2018. PMID: 30158301 Free PMC article. Review.
Drug Discovery for Kinetoplastid Diseases: Future Directions.
Rao SPS, Barrett MP, Dranoff G, Faraday CJ, Gimpelewicz CR, Hailu A, Jones CL, Kelly JM, Lazdins-Helds JK, Mäser P, Mengel J, Mottram JC, Mowbray CE, Sacks DL, Scott P, Späth GF, Tarleton RL, Spector JM, Diagana TT. Rao SPS, et al. Among authors: mowbray ce. ACS Infect Dis. 2019 Feb 8;5(2):152-157. doi: 10.1021/acsinfecdis.8b00298. Epub 2018 Dec 13. ACS Infect Dis. 2019. PMID: 30543391 Free article.
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
Mowbray CE, Braillard S, Glossop PA, Whitlock GA, Jacobs RT, Speake J, Pandi B, Nare B, Maes L, Yardley V, Freund Y, Wall RJ, Carvalho S, Bello D, Van den Kerkhof M, Caljon G, Gilbert IH, Corpas-Lopez V, Lukac I, Patterson S, Zuccotto F, Wyllie S. Mowbray CE, et al. J Med Chem. 2021 Nov 11;64(21):16159-16176. doi: 10.1021/acs.jmedchem.1c01437. Epub 2021 Oct 28. J Med Chem. 2021. PMID: 34711050 Free PMC article.
[NTD Drug Discovery Booster, Achievements and Next Steps].
Kuzuki T, Perry B, Mowbray C. Kuzuki T, et al. Among authors: mowbray c. Yakugaku Zasshi. 2022;142(7):685-689. doi: 10.1248/yakushi.21-00210-1. Yakugaku Zasshi. 2022. PMID: 35781494 Free article. Japanese.
Collaborative Virtual Screening Identifies a 2-Aryl-4-aminoquinazoline Series with Efficacy in an In Vivo Model of Trypanosoma cruzi Infection.
Tawaraishi T, Ochida A, Akao Y, Itono S, Kamaura M, Akther T, Shimada M, Canan S, Chowdhury S, Cao Y, Condroski K, Engkvist O, Francisco A, Ghosh S, Kaki R, Kelly JM, Kimura C, Kogej T, Nagaoka K, Naito A, Pairaudeau G, Radu C, Roberts I, Shum D, Watanabe NA, Xie H, Yonezawa S, Yoshida O, Yoshida R, Mowbray C, Perry B. Tawaraishi T, et al. Among authors: mowbray c. J Med Chem. 2023 Jan 26;66(2):1221-1238. doi: 10.1021/acs.jmedchem.2c00775. Epub 2023 Jan 6. J Med Chem. 2023. PMID: 36607408 Free PMC article.
Pyrazole NNRTIs 3: optimisation of physicochemical properties.
Mowbray CE, Corbau R, Hawes M, Jones LH, Mills JE, Perros M, Selby MD, Stupple PA, Webster R, Wood A. Mowbray CE, et al. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5603-6. doi: 10.1016/j.bmcl.2009.08.043. Epub 2009 Aug 14. Bioorg Med Chem Lett. 2009. PMID: 19717303
Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis.
Caridha D, Vesely B, van Bocxlaer K, Arana B, Mowbray CE, Rafati S, Uliana S, Reguera R, Kreishman-Deitrick M, Sciotti R, Buffet P, Croft SL. Caridha D, et al. Int J Parasitol Drugs Drug Resist. 2019 Dec;11:106-117. doi: 10.1016/j.ijpddr.2019.06.003. Epub 2019 Jun 20. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31320296 Free PMC article. Review.
179 results