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Page 1
Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.
Khabirova E, Jardine L, Coorens THH, Webb S, Treger TD, Engelbert J, Porter T, Prigmore E, Collord G, Piapi A, Teichmann SA, Inglott S, Williams O, Heidenreich O, Young MD, Straathof K, Bomken S, Bartram J, Haniffa M, Behjati S. Khabirova E, et al. Among authors: piapi a. Nat Med. 2022 Apr;28(4):743-751. doi: 10.1038/s41591-022-01720-7. Epub 2022 Mar 14. Nat Med. 2022. PMID: 35288693 Free PMC article.
Single cell derived mRNA signals across human kidney tumors.
Young MD, Mitchell TJ, Custers L, Margaritis T, Morales-Rodriguez F, Kwakwa K, Khabirova E, Kildisiute G, Oliver TRW, de Krijger RR, van den Heuvel-Eibrink MM, Comitani F, Piapi A, Bugallo-Blanco E, Thevanesan C, Burke C, Prigmore E, Ambridge K, Roberts K, Braga FAV, Coorens THH, Del Valle I, Wilbrey-Clark A, Mamanova L, Stewart GD, Gnanapragasam VJ, Rampling D, Sebire N, Coleman N, Hook L, Warren A, Haniffa M, Kool M, Pfister SM, Achermann JC, He X, Barker RA, Shlien A, Bayraktar OA, Teichmann SA, Holstege FC, Meyer KB, Drost J, Straathof K, Behjati S. Young MD, et al. Among authors: piapi a. Nat Commun. 2021 Jun 23;12(1):3896. doi: 10.1038/s41467-021-23949-5. Nat Commun. 2021. PMID: 34162837 Free PMC article.
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.
Kildisiute G, Kholosy WM, Young MD, Roberts K, Elmentaite R, van Hooff SR, Pacyna CN, Khabirova E, Piapi A, Thevanesan C, Bugallo-Blanco E, Burke C, Mamanova L, Keller KM, Langenberg-Ververgaert KPS, Lijnzaad P, Margaritis T, Holstege FCP, Tas ML, Wijnen MHWA, van Noesel MM, Del Valle I, Barone G, van der Linden R, Duncan C, Anderson J, Achermann JC, Haniffa M, Teichmann SA, Rampling D, Sebire NJ, He X, de Krijger RR, Barker RA, Meyer KB, Bayraktar O, Straathof K, Molenaar JJ, Behjati S. Kildisiute G, et al. Among authors: piapi a. Sci Adv. 2021 Feb 5;7(6):eabd3311. doi: 10.1126/sciadv.abd3311. Print 2021 Feb. Sci Adv. 2021. PMID: 33547074 Free PMC article.
Tunable control of CAR T cell activity through tetracycline mediated disruption of protein-protein interaction.
Hotblack A, Kokalaki EK, Palton MJ, Cheung GW, Williams IP, Manzoor S, Grothier TI, Piapi A, Fiaccadori V, Wawrzyniecka P, Roddy HA, Agliardi G, Roddie C, Onuoha S, Thomas S, Cordoba S, Pule M. Hotblack A, et al. Among authors: piapi a. Sci Rep. 2021 Nov 9;11(1):21902. doi: 10.1038/s41598-021-01418-9. Sci Rep. 2021. PMID: 34754016 Free PMC article.
HOX gene expression in the developing human spine.
Lawrence JEG, Roberts K, Tuck E, Li T, Mamanova L, Balogh P, Usher I, Piapi A, Mazin P, Anderson ND, Bolt L, Richardson L, Prigmore E, He X, Barker RA, Flanagan A, Young MD, Teichmann SA, Bayraktar O, Behjati S. Lawrence JEG, et al. Among authors: piapi a. Nat Commun. 2024 Nov 20;15(1):10023. doi: 10.1038/s41467-024-54187-0. Nat Commun. 2024. PMID: 39567486 Free PMC article.
Single-cell transcriptomics identifies aberrant glomerular angiogenic signalling in the early stages of WT1 kidney disease.
Chandler JC, Jafree DJ, Malik S, Pomeranz G, Ball M, Kolatsi-Joannou M, Piapi A, Mason WJ, Benest AV, Bates DO, Letunovska A, Al-Saadi R, Rabant M, Boyer O, Pritchard-Jones K, Winyard PJ, Mason AS, Woolf AS, Waters AM, Long DA. Chandler JC, et al. Among authors: piapi a. J Pathol. 2024 Oct;264(2):212-227. doi: 10.1002/path.6339. Epub 2024 Aug 23. J Pathol. 2024. PMID: 39177649
Transcriptional signals of transformation in human cancer.
Kildisiute G, Kalyva M, Elmentaite R, van Dongen S, Thevanesan C, Piapi A, Ambridge K, Prigmore E, Haniffa M, Teichmann SA, Straathof K, Cortés-Ciriano I, Behjati S, Young MD. Kildisiute G, et al. Among authors: piapi a. Genome Med. 2024 Jan 9;16(1):8. doi: 10.1186/s13073-023-01279-z. Genome Med. 2024. PMID: 38195504 Free PMC article.
Targeting of low ALK antigen density neuroblastoma using AND logic-gate engineered CAR-T cells.
Halliwell E, Vitali A, Muller H, Alonso-Ferrero M, Barisa M, Gavriil A, Piapi A, Leboreiro-Babe C, Gileadi T, Yeung J, Pataillot-Meakin T, Fisher J, Tucker L, Donovan L, Chesler L, Chester K, Anderson J. Halliwell E, et al. Among authors: piapi a. Cytotherapy. 2023 Jan;25(1):46-58. doi: 10.1016/j.jcyt.2022.10.007. Epub 2022 Nov 14. Cytotherapy. 2023. PMID: 36396552 Free article.