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Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.
Khabirova E, Jardine L, Coorens THH, Webb S, Treger TD, Engelbert J, Porter T, Prigmore E, Collord G, Piapi A, Teichmann SA, Inglott S, Williams O, Heidenreich O, Young MD, Straathof K, Bomken S, Bartram J, Haniffa M, Behjati S. Khabirova E, et al. Among authors: williams o. Nat Med. 2022 Apr;28(4):743-751. doi: 10.1038/s41591-022-01720-7. Epub 2022 Mar 14. Nat Med. 2022. PMID: 35288693 Free PMC article.
In focus: MLL-rearranged leukemia.
de Boer J, Walf-Vorderwülbecke V, Williams O. de Boer J, et al. Among authors: williams o. Leukemia. 2013 Jun;27(6):1224-8. doi: 10.1038/leu.2013.78. Epub 2013 Mar 21. Leukemia. 2013. PMID: 23515098 Review.
Targeting acute myeloid leukemia by drug-induced c-MYB degradation.
Walf-Vorderwülbecke V, Pearce K, Brooks T, Hubank M, van den Heuvel-Eibrink MM, Zwaan CM, Adams S, Edwards D, Bartram J, Samarasinghe S, Ancliff P, Khwaja A, Goulden N, Williams G, de Boer J, Williams O. Walf-Vorderwülbecke V, et al. Among authors: williams o, williams g. Leukemia. 2018 Apr;32(4):882-889. doi: 10.1038/leu.2017.317. Epub 2017 Nov 1. Leukemia. 2018. PMID: 29089643
Identification of a c-MYB-directed therapeutic for acute myeloid leukemia.
Clesham K, Walf-Vorderwülbecke V, Gasparoli L, Virely C, Cantilena S, Tsakaneli A, Inglott S, Adams S, Samarasinghe S, Bartram J, Williams G, de Boer J, Williams O. Clesham K, et al. Among authors: williams o, williams g. Leukemia. 2022 Jun;36(6):1541-1549. doi: 10.1038/s41375-022-01554-9. Epub 2022 Apr 2. Leukemia. 2022. PMID: 35368048 Free PMC article.
Anti-CCR9 chimeric antigen receptor T cells for T-cell acute lymphoblastic leukemia.
Maciocia PM, Wawrzyniecka PA, Maciocia NC, Burley A, Karpanasamy T, Devereaux S, Hoekx M, O'Connor D, Leon T, Rapoz-D'Silva T, Pocock R, Rahman S, Gritti G, Yánez DC, Ross S, Crompton T, Williams O, Lee L, Pule MA, Mansour MR. Maciocia PM, et al. Among authors: o connor d, williams o. Blood. 2022 Jul 7;140(1):25-37. doi: 10.1182/blood.2021013648. Blood. 2022. PMID: 35507686 Free article.
930 results