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A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19.
McElvaney OJ, McEvoy NL, Boland F, McElvaney OF, Hogan G, Donnelly K, Friel O, Browne E, Fraughen DD, Murphy MP, Clarke J, Choileáin ON, O'Connor E, McGuinness R, Boylan M, Kelly A, Hayden JC, Collins AM, Cullen A, Hyland D, Carroll TP, Geoghegan P, Laffey JG, Hennessy M, Martin-Loeches I, McElvaney NG, Curley GF. McElvaney OJ, et al. Med. 2022 Apr 8;3(4):233-248.e6. doi: 10.1016/j.medj.2022.03.001. Epub 2022 Mar 11. Med. 2022. PMID: 35291694 Free PMC article. Clinical Trial.
Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation.
Ward SE, Curley GF, Lavin M, Fogarty H, Karampini E, McEvoy NL, Clarke J, Boylan M, Alalqam R, Worrall AP, Kelly C, de Barra E, Glavey S, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Townsend L, Mallon PW, O'Sullivan JM, O'Donnell JS; Irish COVID-19 Vasculopathy Study (ICVS) Investigators. Ward SE, et al. Br J Haematol. 2021 Feb;192(4):714-719. doi: 10.1111/bjh.17273. Epub 2020 Dec 16. Br J Haematol. 2021. PMID: 33326604 Free article.
A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structured summary of a study protocol for a randomised, controlled trial.
McEvoy NL, Clarke JL, Mc Elvaney OJ, Mc Elvaney OF, Boland F, Hyland D, Geoghegan P, Donnelly K, Friel O, Cullen A, Collins AM, Fraughen D, Martin-Loeches I, Hennessy M, Laffey JG, Mc Elvaney NG, Curley GF. McEvoy NL, et al. Trials. 2021 Apr 19;22(1):288. doi: 10.1186/s13063-021-05254-0. Trials. 2021. PMID: 33874981 Free PMC article.
Pulmonary immuno-thrombosis in COVID-19 ARDS pathogenesis.
O'Donnell JS, Peyvandi F, Martin-Loeches I. O'Donnell JS, et al. Intensive Care Med. 2021 Aug;47(8):899-902. doi: 10.1007/s00134-021-06419-w. Epub 2021 May 30. Intensive Care Med. 2021. PMID: 34052905 Free PMC article. No abstract available.
ADAMTS13 regulation of VWF multimer distribution in severe COVID-19.
Ward SE, Fogarty H, Karampini E, Lavin M, Schneppenheim S, Dittmer R, Morrin H, Glavey S, Ni Cheallaigh C, Bergin C, Martin-Loeches I, Mallon PW, Curley GF, Baker RI, Budde U, O'Sullivan JM, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Ward SE, et al. J Thromb Haemost. 2021 Aug;19(8):1914-1921. doi: 10.1111/jth.15409. Epub 2021 Jun 20. J Thromb Haemost. 2021. PMID: 34053187 Free PMC article.
Mortality associated with early changes in ARDS severity in COVID-19 patients - Insights from the PRoVENT-COVID study.
Schuijt MTU, Martin-Loeches I, Schultz MJ, Paulus F, Neto AS; PRoVENT-COVID; PRoVENT-COVID Collaborative Group members. Electronic address: [email protected]; PRoVENT-COVID Collaborative Group members. Schuijt MTU, et al. J Crit Care. 2021 Oct;65:237-245. doi: 10.1016/j.jcrc.2021.06.016. Epub 2021 Jul 7. J Crit Care. 2021. PMID: 34271294 Free PMC article.
Persistent endotheliopathy in the pathogenesis of long COVID syndrome.
Fogarty H, Townsend L, Morrin H, Ahmad A, Comerford C, Karampini E, Englert H, Byrne M, Bergin C, O'Sullivan JM, Martin-Loeches I, Nadarajan P, Bannan C, Mallon PW, Curley GF, Preston RJS, Rehill AM, McGonagle D, Ni Cheallaigh C, Baker RI, Renné T, Ward SE, O'Donnell JS; Irish COVID-19 Vasculopathy Study (iCVS) investigators. Fogarty H, et al. J Thromb Haemost. 2021 Oct;19(10):2546-2553. doi: 10.1111/jth.15490. Epub 2021 Sep 12. J Thromb Haemost. 2021. PMID: 34375505 Free PMC article.
570 results