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Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
EBioMedicine. 2022 Mar;77:103912. doi: 10.1016/j.ebiom.2022.103912. Epub 2022 Mar 13.
EBioMedicine. 2022.
PMID: 35292270
Free PMC article.
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3.
Tripathi U, Nchioua R, Prata LGPL, Zhu Y, Gerdes EOW, Giorgadze N, Pirtskhalava T, Parker E, Xue A, Espindola-Netto JM, Stenger S, Robbins PD, Niedernhofer LJ, Dickinson SL, Allison DB, Kirchhoff F, Sparrer KMJ, Tchkonia T, Kirkland JL.
Tripathi U, et al. Among authors: gerdes eow.
Aging (Albany NY). 2021 Sep 16;13(18):21838-21854. doi: 10.18632/aging.203560. Epub 2021 Sep 16.
Aging (Albany NY). 2021.
PMID: 34531331
Free PMC article.
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Development of a novel senolytic by precise disruption of FOXO4-p53 complex.
Tripathi U, Chaib S, Gerdes EOW, Hogan KA, Zhu Y.
Tripathi U, et al. Among authors: gerdes eow.
EBioMedicine. 2021 Dec;74:103693. doi: 10.1016/j.ebiom.2021.103693. Epub 2021 Nov 9.
EBioMedicine. 2021.
PMID: 34768086
Free PMC article.
No abstract available.
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Community paramedic hospital reduction and mitigation program: study protocol for a randomized pragmatic clinical trial.
Ridgeway JL, Gerdes EOW, Dodge A, Liedl CP, Juntunen MB, Sundt WJS, Glasgow A, Lampman MA, Fink AL, Severson SB, Lin G, Sampson RR, Peterson RP, Murley BM, Klassen AB, Luke A, Friedman PA, Buechler TE, Newman JS, McCoy RG.
Ridgeway JL, et al. Among authors: gerdes eow.
Trials. 2023 Feb 20;24(1):122. doi: 10.1186/s13063-022-07034-w.
Trials. 2023.
PMID: 36805692
Free PMC article.
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