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IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.
Tahtinen S, Tong AJ, Himmels P, Oh J, Paler-Martinez A, Kim L, Wichner S, Oei Y, McCarron MJ, Freund EC, Amir ZA, de la Cruz CC, Haley B, Blanchette C, Schartner JM, Ye W, Yadav M, Sahin U, Delamarre L, Mellman I. Tahtinen S, et al. Among authors: blanchette c. Nat Immunol. 2022 Apr;23(4):532-542. doi: 10.1038/s41590-022-01160-y. Epub 2022 Mar 24. Nat Immunol. 2022. PMID: 35332327
Case report: A persistently expanded T cell response in an exceptional responder to radiation and atezolizumab for metastatic non-small cell lung cancer.
Coffey DG, Xu Y, Towlerton AMH, Kowanetz M, Hegde P, Darwish M, Yadav M, Blanchette C, Ruppert SM, Bertino S, Xu Q, Ferretti A, Weinheimer A, Hellmann M, Qin A, Thomas D, Warren EH, Ramnath N. Coffey DG, et al. Among authors: blanchette c. Front Immunol. 2022 Sep 9;13:961105. doi: 10.3389/fimmu.2022.961105. eCollection 2022. Front Immunol. 2022. PMID: 36159875 Free PMC article.
Systematic discovery of neoepitope-HLA pairs for neoantigens shared among patients and tumor types.
Gurung HR, Heidersbach AJ, Darwish M, Chan PPF, Li J, Beresini M, Zill OA, Wallace A, Tong AJ, Hascall D, Torres E, Chang A, Lou K', Abdolazimi Y, Hammer C, Xavier-Magalhães A, Marcu A, Vaidya S, Le DD, Akhmetzyanova I, Oh SA, Moore AJ, Uche UN, Laur MB, Notturno RJ, Ebert PJR, Blanchette C, Haley B, Rose CM. Gurung HR, et al. Among authors: blanchette c. Nat Biotechnol. 2024 Jul;42(7):1107-1117. doi: 10.1038/s41587-023-01945-y. Epub 2023 Oct 19. Nat Biotechnol. 2024. PMID: 37857725 Free PMC article.
Towards designing improved cancer immunotherapy targets with a peptide-MHC-I presentation model, HLApollo.
Thrift WJ, Lounsbury NW, Broadwell Q, Heidersbach A, Freund E, Abdolazimi Y, Phung QT, Chen J, Capietto AH, Tong AJ, Rose CM, Blanchette C, Lill JR, Haley B, Delamarre L, Bourgon R, Liu K, Jhunjhunwala S. Thrift WJ, et al. Among authors: blanchette c. Nat Commun. 2024 Dec 30;15(1):10752. doi: 10.1038/s41467-024-54887-7. Nat Commun. 2024. PMID: 39737928 Free PMC article.
Nanolipoprotein Particles as a Delivery Platform for Fab Based Therapeutics.
Darwish M, Shatz W, Leonard B, Loyet K, Barrett K, Wong JL, Li H, Abraham R, Lin M, Franke Y, Tam C, Mortara K, Zilberleyb I, Blanchette C. Darwish M, et al. Among authors: blanchette c. Bioconjug Chem. 2020 Aug 19;31(8):1995-2007. doi: 10.1021/acs.bioconjchem.0c00349. Epub 2020 Aug 5. Bioconjug Chem. 2020. PMID: 32701261
231 results