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Page 1
Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics.
Wyler E, Adler JM, Eschke K, Teixeira Alves G, Peidli S, Pott F, Kazmierski J, Michalick L, Kershaw O, Bushe J, Andreotti S, Pennitz P, Abdelgawad A, Postmus D, Goffinet C, Kreye J, Reincke SM, Prüss H, Blüthgen N, Gruber AD, Kuebler WM, Witzenrath M, Landthaler M, Nouailles G, Trimpert J. Wyler E, et al. Among authors: kazmierski j. Mol Ther. 2022 May 4;30(5):1952-1965. doi: 10.1016/j.ymthe.2022.03.014. Epub 2022 Mar 24. Mol Ther. 2022. PMID: 35339689 Free PMC article.
COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis.
Chua RL, Lukassen S, Trump S, Hennig BP, Wendisch D, Pott F, Debnath O, Thürmann L, Kurth F, Völker MT, Kazmierski J, Timmermann B, Twardziok S, Schneider S, Machleidt F, Müller-Redetzky H, Maier M, Krannich A, Schmidt S, Balzer F, Liebig J, Loske J, Suttorp N, Eils J, Ishaque N, Liebert UG, von Kalle C, Hocke A, Witzenrath M, Goffinet C, Drosten C, Laudi S, Lehmann I, Conrad C, Sander LE, Eils R. Chua RL, et al. Among authors: kazmierski j. Nat Biotechnol. 2020 Aug;38(8):970-979. doi: 10.1038/s41587-020-0602-4. Epub 2020 Jun 26. Nat Biotechnol. 2020. PMID: 32591762
Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19.
Trump S, Lukassen S, Anker MS, Chua RL, Liebig J, Thürmann L, Corman VM, Binder M, Loske J, Klasa C, Krieger T, Hennig BP, Messingschlager M, Pott F, Kazmierski J, Twardziok S, Albrecht JP, Eils J, Hadzibegovic S, Lena A, Heidecker B, Bürgel T, Steinfeldt J, Goffinet C, Kurth F, Witzenrath M, Völker MT, Müller SD, Liebert UG, Ishaque N, Kaderali L, Sander LE, Drosten C, Laudi S, Eils R, Conrad C, Landmesser U, Lehmann I. Trump S, et al. Among authors: kazmierski j. Nat Biotechnol. 2021 Jun;39(6):705-716. doi: 10.1038/s41587-020-00796-1. Epub 2020 Dec 24. Nat Biotechnol. 2021. PMID: 33361824
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19.
Nouailles G, Wyler E, Pennitz P, Postmus D, Vladimirova D, Kazmierski J, Pott F, Dietert K, Muelleder M, Farztdinov V, Obermayer B, Wienhold SM, Andreotti S, Hoefler T, Sawitzki B, Drosten C, Sander LE, Suttorp N, Ralser M, Beule D, Gruber AD, Goffinet C, Landthaler M, Trimpert J, Witzenrath M. Nouailles G, et al. Among authors: kazmierski j. Nat Commun. 2021 Aug 11;12(1):4869. doi: 10.1038/s41467-021-25030-7. Nat Commun. 2021. PMID: 34381043 Free PMC article.
SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis.
Wendisch D, Dietrich O, Mari T, von Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D; Deutsche COVID-19 OMICS Initiative (DeCOI); Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba AE, Sander LE. Wendisch D, et al. Among authors: kazmierski j. Cell. 2021 Dec 22;184(26):6243-6261.e27. doi: 10.1016/j.cell.2021.11.033. Epub 2021 Nov 27. Cell. 2021. PMID: 34914922 Free PMC article.
Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization.
Ebenig A, Muraleedharan S, Kazmierski J, Todt D, Auste A, Anzaghe M, Gömer A, Postmus D, Gogesch P, Niles M, Plesker R, Miskey C, Gellhorn Serra M, Breithaupt A, Hörner C, Kruip C, Ehmann R, Ivics Z, Waibler Z, Pfaender S, Wyler E, Landthaler M, Kupke A, Nouailles G, Goffinet C, Brown RJP, Mühlebach MD. Ebenig A, et al. Among authors: kazmierski j. Cell Rep. 2022 Aug 16;40(7):111214. doi: 10.1016/j.celrep.2022.111214. Epub 2022 Aug 3. Cell Rep. 2022. PMID: 35952673 Free PMC article.
Nonproductive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immune responses.
Kazmierski J, Friedmann K, Postmus D, Emanuel J, Fischer C, Jansen J, Richter A, Bosquillon de Jarcy L, Schüler C, Sohn M, Sauer S, Drosten C, Saliba AE, Sander LE, Müller MA, Niemeyer D, Goffinet C. Kazmierski J, et al. Mol Syst Biol. 2022 Aug;18(8):e10961. doi: 10.15252/msb.202210961. Mol Syst Biol. 2022. PMID: 35975552 Free PMC article.
Dysfunctional purinergic signaling correlates with disease severity in COVID-19 patients.
Pietrobon AJ, Andrejew R, Custódio RWA, Oliveira LM, Scholl JN, Teixeira FME, de Brito CA, Glaser T, Kazmierski J, Goffinet C, Turdo AC, Yendo T, Aoki V, Figueiró F, Battastini AM, Ulrich H, Benard G, Duarte AJDS, Sato MN. Pietrobon AJ, et al. Among authors: kazmierski j. Front Immunol. 2022 Sep 30;13:1012027. doi: 10.3389/fimmu.2022.1012027. eCollection 2022. Front Immunol. 2022. PMID: 36248842 Free PMC article.
54 results