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An antibody that inhibits TGF-β1 release from latent extracellular matrix complexes attenuates the progression of renal fibrosis.
Jackson JW, Frederick C Streich Jr, Pal A, Coricor G, Boston C, Brueckner CT, Canonico K, Chapron C, Cote S, Dagbay KB, Danehy FT Jr, Kavosi M, Kumar S, Lin S, Littlefield C, Looby K, Manohar R, Martin CJ, Wood M, Zawadzka A, Wawersik S, Nicholls SB, Datta A, Buckler A, Schürpf T, Carven GJ, Qatanani M, Fogel AI. Jackson JW, et al. Among authors: nicholls sb. Sci Signal. 2024 Jul 9;17(844):eadn6052. doi: 10.1126/scisignal.adn6052. Epub 2024 Jul 9. Sci Signal. 2024. PMID: 38980922
Risk-Based Control Strategies of Recombinant Monoclonal Antibody Charge Variants.
Beck A, Nowak C, Meshulam D, Reynolds K, Chen D, Pacardo DB, Nicholls SB, Carven GJ, Gu Z, Fang J, Wang D, Katiyar A, Xiang T, Liu H. Beck A, et al. Among authors: nicholls sb. Antibodies (Basel). 2022 Nov 20;11(4):73. doi: 10.3390/antib11040073. Antibodies (Basel). 2022. PMID: 36412839 Free PMC article. Review.
U.S. bound journey of migrant peoples InTransit across Dante's Inferno and Purgatory in the Americas.
Higuita NA, Suarez JA, Millender E, Creighton EG, Corbisiero MF, Freites CO, Cordero JH, Kousari A, Unterborn R, Marcos LA, Henao-Martínez AF, Jhangimal M, Pon AY, Tuells J, Gonzalez-Díaz E, Franco-Paredes C, Erausquin JT, Pinzon-Espinosa J, Baird M, Pachar-Flores M, Ordaz M, Cabezas-Talavero G, Katz J, Gonzalez JA, Obando R, Alvarez FR, Naranjo L, Madrid A, Pecchio I, Vistica G, Nakad C, Reina A, Díaz Y, Chen RR, Meng M, Alvarado YW, Nicholls SB, Sanchez J, Rincὁn T, Viquez D, Owen D, Pascale JM, Gabster A; Migrant Peoples in Transit Study Group. Higuita NA, et al. Among authors: nicholls sb. Travel Med Infect Dis. 2022 May-Jun;47:102317. doi: 10.1016/j.tmaid.2022.102317. Epub 2022 Mar 24. Travel Med Infect Dis. 2022. PMID: 35342009
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients.
Takeda S, Commins C, DeVos SL, Nobuhara CK, Wegmann S, Roe AD, Costantino I, Fan Z, Nicholls SB, Sherman AE, Trisini Lipsanopoulos AT, Scherzer CR, Carlson GA, Pitstick R, Peskind ER, Raskind MA, Li G, Montine TJ, Frosch MP, Hyman BT. Takeda S, et al. Among authors: nicholls sb. Ann Neurol. 2016 Sep;80(3):355-67. doi: 10.1002/ana.24716. Epub 2016 Aug 3. Ann Neurol. 2016. PMID: 27351289 Free PMC article.
Hypothermia mediates age-dependent increase of tau phosphorylation in db/db mice.
El Khoury NB, Gratuze M, Petry F, Papon MA, Julien C, Marcouiller F, Morin F, Nicholls SB, Calon F, Hébert SS, Marette A, Planel E. El Khoury NB, et al. Among authors: nicholls sb. Neurobiol Dis. 2016 Apr;88:55-65. doi: 10.1016/j.nbd.2016.01.005. Epub 2016 Jan 9. Neurobiol Dis. 2016. PMID: 26777665
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