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A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection.
Routhu NK, Gangadhara S, Lai L, Davis-Gardner ME, Floyd K, Shiferaw A, Bartsch YC, Fischinger S, Khoury G, Rahman SA, Stampfer SD, Schäfer A, Jean SM, Wallace C, Stammen RL, Wood J, Joyce C, Nagy T, Parsons MS, Gralinski L, Kozlowski PA, Alter G, Suthar MS, Amara RR. Routhu NK, et al. Among authors: alter g. Sci Immunol. 2022 Jun 24;7(72):eabo0226. doi: 10.1126/sciimmunol.abo0226. Epub 2022 Jun 24. Sci Immunol. 2022. PMID: 35357886 Free PMC article.
Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys.
Abbink P, Larocca RA, De La Barrera RA, Bricault CA, Moseley ET, Boyd M, Kirilova M, Li Z, Ng'ang'a D, Nanayakkara O, Nityanandam R, Mercado NB, Borducchi EN, Agarwal A, Brinkman AL, Cabral C, Chandrashekar A, Giglio PB, Jetton D, Jimenez J, Lee BC, Mojta S, Molloy K, Shetty M, Neubauer GH, Stephenson KE, Peron JP, Zanotto PM, Misamore J, Finneyfrock B, Lewis MG, Alter G, Modjarrad K, Jarman RG, Eckels KH, Michael NL, Thomas SJ, Barouch DH. Abbink P, et al. Among authors: alter g. Science. 2016 Sep 9;353(6304):1129-32. doi: 10.1126/science.aah6157. Epub 2016 Aug 4. Science. 2016. PMID: 27492477 Free PMC article.
Analysis of Complement-Mediated Lysis of Simian Immunodeficiency Virus (SIV) and SIV-Infected Cells Reveals Sex Differences in Vaccine-Induced Immune Responses in Rhesus Macaques.
Miller-Novak LK, Das J, Musich TA, Demberg T, Weiner JA, Venzon DJ, Mohanram V, Vargas-Inchaustegui DA, Tuero I, Ackerman ME, Alter G, Robert-Guroff M. Miller-Novak LK, et al. Among authors: alter g. J Virol. 2018 Sep 12;92(19):e00721-18. doi: 10.1128/JVI.00721-18. Print 2018 Oct 1. J Virol. 2018. PMID: 30021899 Free PMC article.
Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.
Lofano G, Gorman MJ, Yousif AS, Yu WH, Fox JM, Dugast AS, Ackerman ME, Suscovich TJ, Weiner J, Barouch D, Streeck H, Little S, Smith D, Richman D, Lauffenburger D, Walker BD, Diamond MS, Alter G. Lofano G, et al. Among authors: alter g. Sci Immunol. 2018 Aug 17;3(26):eaat7796. doi: 10.1126/sciimmunol.aat7796. Sci Immunol. 2018. PMID: 30120121 Free PMC article.
Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.
Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, Hesselgesser J, Li W, Lewis MG, Alter G, Geleziunas R, Barouch DH. Borducchi EN, et al. Among authors: alter g. Nature. 2018 Nov;563(7731):360-364. doi: 10.1038/s41586-018-0600-6. Epub 2018 Oct 3. Nature. 2018. PMID: 30283138 Free PMC article.
Vectored delivery of anti-SIV envelope targeting mAb via AAV8 protects rhesus macaques from repeated limiting dose intrarectal swarm SIVsmE660 challenge.
Welles HC, Jennewein MF, Mason RD, Narpala S, Wang L, Cheng C, Zhang Y, Todd JP, Lifson JD, Balazs AB, Alter G, McDermott AB, Mascola JR, Roederer M. Welles HC, et al. Among authors: alter g. PLoS Pathog. 2018 Dec 5;14(12):e1007395. doi: 10.1371/journal.ppat.1007395. eCollection 2018 Dec. PLoS Pathog. 2018. PMID: 30517201 Free PMC article.
Sex differences in vaccine-induced humoral immunity.
Fischinger S, Boudreau CM, Butler AL, Streeck H, Alter G. Fischinger S, et al. Among authors: alter g. Semin Immunopathol. 2019 Mar;41(2):239-249. doi: 10.1007/s00281-018-0726-5. Epub 2018 Dec 13. Semin Immunopathol. 2019. PMID: 30547182 Free PMC article. Review.
The Antibodiome-Mapping the Humoral Immune Response to HIV.
Butler AL, Fischinger S, Alter G. Butler AL, et al. Among authors: alter g. Curr HIV/AIDS Rep. 2019 Apr;16(2):169-179. doi: 10.1007/s11904-019-00432-x. Curr HIV/AIDS Rep. 2019. PMID: 30903381 Free PMC article. Review.
627 results