Cao X - Search Results

1

Long Residence Time at the Vasopressin V₂ Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease.

Zhang H, Yan W, Sun Y, Yuan H, Su L, Cao X, Wang P, Xu Z, Hu Y, Wang Z, Wang Y, Fu K, Sun Y, Chen Y, Cheng J, Guo D. Zhang H, et al. Among authors: cao x. J Med Chem. 2022 Jun 9;65(11):7717-7728. doi: 10.1021/acs.jmedchem.2c00011. Epub 2022 Apr 1. J Med Chem. 2022. PMID: 35363466

2

Revisit ligand-receptor interaction at the human vasopressin V₂ receptor: A kinetic perspective.

Liu C, Xia L, Fu K, Cao X, Yan W, Cheng J, Roux T, Peletier LA, Yin X, Guo D. Liu C, et al. Among authors: cao x. Eur J Pharmacol. 2020 Aug 5;880:173157. doi: 10.1016/j.ejphar.2020.173157. Epub 2020 Apr 30. Eur J Pharmacol. 2020. PMID: 32360346

3

Isoquinolinone derivatives as potent CNS multi-receptor D₂/5-HT_1A/5-HT_2A/5-HT₆/5-HT₇ agents: Synthesis and pharmacological evaluation.

Jin J, Zhang K, Dou F, Hao C, Zhang Y, Cao X, Gao L, Xiong J, Liu X, Liu BF, Zhang G, Chen Y. Jin J, et al. Among authors: cao x. Eur J Med Chem. 2020 Dec 1;207:112709. doi: 10.1016/j.ejmech.2020.112709. Epub 2020 Aug 20. Eur J Med Chem. 2020. PMID: 32877805

4

Benzodiazepine Derivatives as Potent Vasopressin V₂ Receptor Antagonists for the Treatment of Autosomal Dominant Kidney Disease.

Cao X, Wang P, Yuan H, Zhang H, He Y, Fu K, Fang Q, Liu H, Su L, Yin L, Xu P, Xie Y, Xiong X, Wang J, Zhu X, Guo D. Cao X, et al. J Med Chem. 2022 Jul 14;65(13):9295-9311. doi: 10.1021/acs.jmedchem.2c00567. Epub 2022 May 17. J Med Chem. 2022. PMID: 35579344

5

Defluorinative Alkylation of Trifluoromethylbenzimidazoles Enabled by Spin-Center Shift: A Synergistic Photocatalysis/Thiol Catalysis Process with CO₂^•.

Xu P, Wang XY, Wang Z, Zhao J, Cao XD, Xiong XC, Yuan YC, Zhu S, Guo D, Zhu X. Xu P, et al. Among authors: cao xd. Org Lett. 2022 Jun 10;24(22):4075-4080. doi: 10.1021/acs.orglett.2c01533. Epub 2022 Jun 1. Org Lett. 2022. PMID: 35648621

6

Structure-Affinity and Structure-Kinetic Relationship Studies of Benzodiazepine Derivatives for the Development of Efficacious Vasopressin V₂ Receptor Antagonists.

Cao X, Wang P, Zhao W, Yuan H, Hu H, Chen T, Zhang Y, Ren Y, Su L, Fu K, Liu H, Guo D. Cao X, et al. J Med Chem. 2023 Mar 9;66(5):3621-3634. doi: 10.1021/acs.jmedchem.3c00015. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36732931

7

Benzothiazole derivatives as histone deacetylase inhibitors for the treatment of autosomal dominant polycystic kidney disease.

Cao X, Fan Z, Xu L, Zhao W, Zhang H, Yang Y, Ren Y, Xiao Y, Zhou N, Yin L, Zhou X, Zhu X, Guo D. Cao X, et al. Eur J Med Chem. 2024 May 5;271:116428. doi: 10.1016/j.ejmech.2024.116428. Epub 2024 Apr 18. Eur J Med Chem. 2024. PMID: 38653068

8

Structural basis of tolvaptan binding to the vasopressin V₂ receptor.

Liu HL, Zhong HY, Zhang YX, Xue HR, Zhang ZS, Fu KQ, Cao XD, Xiong XC, Guo D. Liu HL, et al. Acta Pharmacol Sin. 2024 Nov;45(11):2441-2449. doi: 10.1038/s41401-024-01325-5. Epub 2024 Jun 20. Acta Pharmacol Sin. 2024. PMID: 38902502

9

Synthesis and Biological Evaluation of Novel σ1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones.

Cao X, Chen Y, Zhang Y, Lan Y, Zhang J, Xu X, Qiu Y, Zhao S, Liu X, Liu BF, Zhang G. Cao X, et al. J Med Chem. 2016 Apr 14;59(7):2942-61. doi: 10.1021/acs.jmedchem.5b01416. Epub 2016 Mar 29. J Med Chem. 2016. PMID: 27003636 Free article.

10

Synthesis and biological evaluation of new 6-hydroxypyridazinone benzisoxazoles: Potential multi-receptor-targeting atypical antipsychotics.

Cao X, Chen Y, Zhang Y, Qiu Y, Yu M, Xu X, Liu X, Liu BF, Zhang G. Cao X, et al. Eur J Med Chem. 2016 Nov 29;124:713-728. doi: 10.1016/j.ejmech.2016.09.008. Epub 2016 Sep 4. Eur J Med Chem. 2016. PMID: 27639363

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