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Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index.
Gurtan A, Dominy J, Khalid S, Vong L, Caplan S, Currie T, Richards S, Lamarche L, Denning D, Shpektor D, Gurinovich A, Rasheed A, Hameed S, Saeed S, Saleem I, Jalal A, Abbas S, Sultana R, Rasheed SZ, Memon FU, Shah N, Ishaq M, Khera AV, Danesh J, Frossard P, Saleheen D. Gurtan A, et al. Among authors: gurinovich a. PLoS Genet. 2022 Apr 5;18(4):e1010093. doi: 10.1371/journal.pgen.1010093. eCollection 2022 Apr. PLoS Genet. 2022. PMID: 35381001 Free PMC article.
Rare genetic variants correlate with better processing speed.
Song Z, Gurinovich A, Nygaard M, Mengel-From J, Andersen S, Cosentino S, Schupf N, Lee J, Zmuda J, Ukraintseva S, Arbeev K, Christensen K, Perls T, Sebastiani P. Song Z, et al. Among authors: gurinovich a. Neurobiol Aging. 2023 May;125:115-122. doi: 10.1016/j.neurobiolaging.2022.11.018. Epub 2023 Jan 29. Neurobiol Aging. 2023. PMID: 36813607 Free PMC article.
yQTL Pipeline: a structured computational workflow for large scale quantitative trait loci discovery and downstream visualization.
Li M, Song Z, Gurinovich A, Schork N, Sebastiani P, Monti S. Li M, et al. Among authors: gurinovich a. bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577518. doi: 10.1101/2024.01.26.577518. bioRxiv. 2024. Update in: PLoS One. 2024 Jun 4;19(6):e0298501. doi: 10.1371/journal.pone.0298501 PMID: 38370654 Free PMC article. Updated. Preprint.
Assortative Mating by Ethnicity in Longevous Families.
Sebastiani P, Gurinovich A, Bae H, Andersen SL, Perls TT. Sebastiani P, et al. Among authors: gurinovich a. Front Genet. 2017 Nov 21;8:186. doi: 10.3389/fgene.2017.00186. eCollection 2017. Front Genet. 2017. PMID: 29209360 Free PMC article.
Limitations and risks of meta-analyses of longevity studies.
Sebastiani P, Bae H, Gurinovich A, Soerensen M, Puca A, Perls TT. Sebastiani P, et al. Among authors: gurinovich a. Mech Ageing Dev. 2017 Jul;165(Pt B):139-146. doi: 10.1016/j.mad.2017.01.008. Epub 2017 Jan 28. Mech Ageing Dev. 2017. PMID: 28143747 Free PMC article. Review.
Four Genome-Wide Association Studies Identify New Extreme Longevity Variants.
Sebastiani P, Gurinovich A, Bae H, Andersen S, Malovini A, Atzmon G, Villa F, Kraja AT, Ben-Avraham D, Barzilai N, Puca A, Perls TT. Sebastiani P, et al. Among authors: gurinovich a. J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1453-1464. doi: 10.1093/gerona/glx027. J Gerontol A Biol Sci Med Sci. 2017. PMID: 28329165 Free PMC article.
APOE Alleles and Extreme Human Longevity.
Sebastiani P, Gurinovich A, Nygaard M, Sasaki T, Sweigart B, Bae H, Andersen SL, Villa F, Atzmon G, Christensen K, Arai Y, Barzilai N, Puca A, Christiansen L, Hirose N, Perls TT. Sebastiani P, et al. Among authors: gurinovich a. J Gerontol A Biol Sci Med Sci. 2019 Jan 1;74(1):44-51. doi: 10.1093/gerona/gly174. J Gerontol A Biol Sci Med Sci. 2019. PMID: 30060062 Free PMC article. Review.
Sex Differences in Genetic Associations With Longevity.
Zeng Y, Nie C, Min J, Chen H, Liu X, Ye R, Chen Z, Bai C, Xie E, Yin Z, Lv Y, Lu J, Li J, Ni T, Bolund L, Land KC, Yashin A, O'Rand AM, Sun L, Yang Z, Tao W, Gurinovich A, Franceschi C, Xie J, Gu J, Hou Y, Liu X, Xu X, Robine JM, Deelen J, Sebastiani P, Slagboom E, Perls T, Hauser E, Gottschalk W, Tan Q, Christensen K, Shi X, Lutz M, Tian XL, Yang H, Vaupel J. Zeng Y, et al. Among authors: gurinovich a. JAMA Netw Open. 2018 Aug;1(4):e181670. doi: 10.1001/jamanetworkopen.2018.1670. Epub 2018 Aug 24. JAMA Netw Open. 2018. PMID: 30294719 Free PMC article.
27 results