Raguram A - Search Results

1

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration.

Choi EH, Suh S, Foik AT, Leinonen H, Newby GA, Gao XD, Banskota S, Hoang T, Du SW, Dong Z, Raguram A, Kohli S, Blackshaw S, Lyon DC, Liu DR, Palczewski K. Choi EH, et al. Among authors: raguram a. Nat Commun. 2022 Apr 5;13(1):1830. doi: 10.1038/s41467-022-29490-3. Nat Commun. 2022. PMID: 35383196 Free PMC article.

2

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.

Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR. Koblan LW, et al. Among authors: raguram a. Nat Biotechnol. 2018 Oct;36(9):843-846. doi: 10.1038/nbt.4172. Epub 2018 May 29. Nat Biotechnol. 2018. PMID: 29813047 Free PMC article.

3

Search-and-replace genome editing without double-strand breaks or donor DNA.

Anzalone AV, Randolph PB, Davis JR, Sousa AA, Koblan LW, Levy JM, Chen PJ, Wilson C, Newby GA, Raguram A, Liu DR. Anzalone AV, et al. Among authors: raguram a. Nature. 2019 Dec;576(7785):149-157. doi: 10.1038/s41586-019-1711-4. Epub 2019 Oct 21. Nature. 2019. PMID: 31634902 Free PMC article.

4

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors.

Doman JL, Raguram A, Newby GA, Liu DR. Doman JL, et al. Among authors: raguram a. Nat Biotechnol. 2020 May;38(5):620-628. doi: 10.1038/s41587-020-0414-6. Epub 2020 Feb 10. Nat Biotechnol. 2020. PMID: 32042165 Free PMC article.

5

Prime genome editing in rice and wheat.

Lin Q, Zong Y, Xue C, Wang S, Jin S, Zhu Z, Wang Y, Anzalone AV, Raguram A, Doman JL, Liu DR, Gao C. Lin Q, et al. Among authors: raguram a. Nat Biotechnol. 2020 May;38(5):582-585. doi: 10.1038/s41587-020-0455-x. Epub 2020 Mar 16. Nat Biotechnol. 2020. PMID: 32393904

6

A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.

Mok BY, de Moraes MH, Zeng J, Bosch DE, Kotrys AV, Raguram A, Hsu F, Radey MC, Peterson SB, Mootha VK, Mougous JD, Liu DR. Mok BY, et al. Among authors: raguram a. Nature. 2020 Jul;583(7817):631-637. doi: 10.1038/s41586-020-2477-4. Epub 2020 Jul 8. Nature. 2020. PMID: 32641830 Free PMC article.

7

Disulfide-compatible phage-assisted continuous evolution in the periplasmic space.

Morrison MS, Wang T, Raguram A, Hemez C, Liu DR. Morrison MS, et al. Among authors: raguram a. Nat Commun. 2021 Oct 13;12(1):5959. doi: 10.1038/s41467-021-26279-8. Nat Commun. 2021. PMID: 34645844 Free PMC article.

8

Author Correction: Disulfide-compatible phage-assisted continuous evolution in the periplasmic space.

Morrison MS, Wang T, Raguram A, Hemez C, Liu DR. Morrison MS, et al. Among authors: raguram a. Nat Commun. 2021 Nov 17;12(1):6800. doi: 10.1038/s41467-021-27102-0. Nat Commun. 2021. PMID: 34789771 Free PMC article. No abstract available.

9

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing.

Anzalone AV, Gao XD, Podracky CJ, Nelson AT, Koblan LW, Raguram A, Levy JM, Mercer JAM, Liu DR. Anzalone AV, et al. Among authors: raguram a. Nat Biotechnol. 2022 May;40(5):731-740. doi: 10.1038/s41587-021-01133-w. Epub 2021 Dec 9. Nat Biotechnol. 2022. PMID: 34887556 Free PMC article.

10

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.

Banskota S, Raguram A, Suh S, Du SW, Davis JR, Choi EH, Wang X, Nielsen SC, Newby GA, Randolph PB, Osborn MJ, Musunuru K, Palczewski K, Liu DR. Banskota S, et al. Among authors: raguram a. Cell. 2022 Jan 20;185(2):250-265.e16. doi: 10.1016/j.cell.2021.12.021. Epub 2022 Jan 11. Cell. 2022. PMID: 35021064 Free PMC article.

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