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CXCL5-mediated accumulation of mature neutrophils in lung cancer tissues impairs the differentiation program of anticancer CD8 T cells and limits the efficacy of checkpoint inhibitors.
Simoncello F, Piperno GM, Caronni N, Amadio R, Cappelletto A, Canarutto G, Piazza S, Bicciato S, Benvenuti F. Simoncello F, et al. Among authors: caronni n. Oncoimmunology. 2022 Apr 7;11(1):2059876. doi: 10.1080/2162402X.2022.2059876. eCollection 2022. Oncoimmunology. 2022. PMID: 35402081 Free PMC article.
Neutrophils drive type I interferon production and autoantibodies in patients with Wiskott-Aldrich syndrome.
Cervantes-Luevano KE, Caronni N, Castiello MC, Fontana E, Piperno GM, Naseem A, Uva P, Bosticardo M, Marcovecchio GE, Notarangelo LD, Cicalese MP, Aiuti A, Villa A, Benvenuti F. Cervantes-Luevano KE, et al. Among authors: caronni n. J Allergy Clin Immunol. 2018 Nov;142(5):1605-1617.e4. doi: 10.1016/j.jaci.2017.11.063. Epub 2018 Feb 13. J Allergy Clin Immunol. 2018. PMID: 29447842 Free PMC article.
Wiskott-Aldrich syndrome protein restricts cGAS/STING activation by dsDNA immune complexes.
Piperno GM, Naseem A, Silvestrelli G, Amadio R, Caronni N, Cervantes-Luevano KE, Liv N, Klumperman J, Colliva A, Ali H, Graziano F, Benaroch P, Haecker H, Hanna RN, Benvenuti F. Piperno GM, et al. Among authors: caronni n. JCI Insight. 2020 Sep 3;5(17):e132857. doi: 10.1172/jci.insight.132857. JCI Insight. 2020. PMID: 32721945 Free PMC article.
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses.
Caronni N, Piperno GM, Simoncello F, Romano O, Vodret S, Yanagihashi Y, Dress R, Dutertre CA, Bugatti M, Bourdeley P, Del Prete A, Schioppa T, Mazza EMC, Collavin L, Zacchigna S, Ostuni R, Guermonprez P, Vermi W, Ginhoux F, Bicciato S, Nagata S, Benvenuti F. Caronni N, et al. Nat Commun. 2021 Apr 14;12(1):2237. doi: 10.1038/s41467-021-22535-z. Nat Commun. 2021. PMID: 33854047 Free PMC article.
A Population of TIM4+FOLR2+ Macrophages Localized in Tertiary Lymphoid Structures Correlates to an Active Immune Infiltrate Across Several Cancer Types.
Bugatti M, Bergamini M, Missale F, Monti M, Ardighieri L, Pezzali I, Picinoli S, Caronni N, Missolo-Koussou Y, Helft J, Benvenuti F, Vermi W. Bugatti M, et al. Among authors: caronni n. Cancer Immunol Res. 2022 Nov 2;10(11):1340-1353. doi: 10.1158/2326-6066.CIR-22-0271. Cancer Immunol Res. 2022. PMID: 36122412
Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.
López L, Morosi LG, La Terza F, Bourdely P, Rospo G, Amadio R, Piperno GM, Russo V, Volponi C, Vodret S, Joshi S, Giannese F, Lazarevic D, Germano G, Stoitzner P, Bardelli A, Dalod M, Pace L, Caronni N, Guermonprez P, Benvenuti F. López L, et al. Among authors: caronni n. Nat Commun. 2024 Mar 13;15(1):2280. doi: 10.1038/s41467-024-46685-y. Nat Commun. 2024. PMID: 38480738 Free PMC article.
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