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Role of Disease Progression Models in Drug Development.
Barrett JS, Nicholas T, Azer K, Corrigan BW. Barrett JS, et al. Pharm Res. 2022 Aug;39(8):1803-1815. doi: 10.1007/s11095-022-03257-3. Epub 2022 Apr 11. Pharm Res. 2022. PMID: 35411507 Free PMC article. Review.
A Quantitative Systems Pharmacology Platform to Investigate the Impact of Alirocumab and Cholesterol-Lowering Therapies on Lipid Profiles and Plaque Characteristics.
Ming JE, Abrams RE, Bartlett DW, Tao M, Nguyen T, Surks H, Kudrycki K, Kadambi A, Friedrich CM, Djebli N, Goebel B, Koszycki A, Varshnaya M, Elassal J, Banerjee P, Sasiela WJ, Reed MJ, Barrett JS, Azer K. Ming JE, et al. Among authors: barrett js. Gene Regul Syst Bio. 2017 Jun 22;11:1177625017710941. doi: 10.1177/1177625017710941. eCollection 2017. Gene Regul Syst Bio. 2017. PMID: 28804243 Free PMC article.
Quantitative Systems Pharmacology Modeling of Acid Sphingomyelinase Deficiency and the Enzyme Replacement Therapy Olipudase Alfa Is an Innovative Tool for Linking Pathophysiology and Pharmacology.
Kaddi CD, Niesner B, Baek R, Jasper P, Pappas J, Tolsma J, Li J, van Rijn Z, Tao M, Ortemann-Renon C, Easton R, Tan S, Puga AC, Schuchman EH, Barrett JS, Azer K. Kaddi CD, et al. Among authors: barrett js. CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):442-452. doi: 10.1002/psp4.12304. Epub 2018 Jun 19. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29920993 Free PMC article.
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat.
Abrams R, Kaddi CD, Tao M, Leiser RJ, Simoni G, Reali F, Tolsma J, Jasper P, van Rijn Z, Li J, Niesner B, Barrett JS, Marchetti L, Peterschmitt MJ, Azer K, Neves-Zaph S. Abrams R, et al. Among authors: barrett js. CPT Pharmacometrics Syst Pharmacol. 2020 Jul;9(7):374-383. doi: 10.1002/psp4.12506. Epub 2020 Jun 19. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32558397 Free PMC article.
History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications.
Azer K, Kaddi CD, Barrett JS, Bai JPF, McQuade ST, Merrill NJ, Piccoli B, Neves-Zaph S, Marchetti L, Lombardo R, Parolo S, Immanuel SRC, Baliga NS. Azer K, et al. Among authors: barrett js. Front Physiol. 2021 Mar 25;12:637999. doi: 10.3389/fphys.2021.637999. eCollection 2021. Front Physiol. 2021. PMID: 33841175 Free PMC article. Review.
235 results