The critical role of the variable domain in driving proteotoxicity and aggregation in full-length light chains.
Puri S, Gadda A, Polsinelli I, Barzago MM, Toto A, Sriramoju MK, Visentin C, Broggini L, Valérie Bonnet DM, Russo R, Chaves-Sanjuan A, Merlini G, Nuvolone M, Palladini G, Gianni S, Hsu SD, Diomede L, Ricagno S.
Puri S, et al.
J Mol Biol. 2025 Jan 20:168958. doi: 10.1016/j.jmb.2025.168958. Online ahead of print.
J Mol Biol. 2025.
PMID: 39842712