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Page 1
Transcriptomic Analysis of the Major Orphan Ichthyosis Subtypes Reveals Shared Immune and Barrier Signatures.
Kim M, Mikhaylov D, Rangel SM, Pavel AB, He H, Renert-Yuval Y, Del Duca E, Malik K, Huynh T, Ibler E, Sun M, Zhang N, Estrada Y, Krueger J, Paller AS, Guttman-Yassky E. Kim M, et al. Among authors: malik k. J Invest Dermatol. 2022 Sep;142(9):2363-2374.e18. doi: 10.1016/j.jid.2022.03.022. Epub 2022 Apr 11. J Invest Dermatol. 2022. PMID: 35421402 Free PMC article.
The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood.
Czarnowicki T, He H, Leonard A, Malik K, Magidi S, Rangel S, Patel K, Ramsey K, Murphrey M, Song T, Estrada Y, Wen HC, Krueger JG, Guttman-Yassky E, Paller AS. Czarnowicki T, et al. Among authors: malik k. J Invest Dermatol. 2018 Oct;138(10):2157-2167. doi: 10.1016/j.jid.2018.03.1523. Epub 2018 Apr 14. J Invest Dermatol. 2018. PMID: 29660300 Free article.
Ichthyosis molecular fingerprinting shows profound TH17 skewing and a unique barrier genomic signature.
Malik K, He H, Huynh TN, Tran G, Mueller K, Doytcheva K, Renert-Yuval Y, Czarnowicki T, Magidi S, Chou M, Estrada YD, Wen HC, Peng X, Xu H, Zheng X, Krueger JG, Paller AS, Guttman-Yassky E. Malik K, et al. J Allergy Clin Immunol. 2019 Feb;143(2):604-618. doi: 10.1016/j.jaci.2018.03.021. Epub 2018 May 24. J Allergy Clin Immunol. 2019. PMID: 29803800 Free PMC article.
A Phase 2 Randomized Trial of Apremilast in Patients with Atopic Dermatitis.
Simpson EL, Imafuku S, Poulin Y, Ungar B, Zhou L, Malik K, Wen HC, Xu H, Estrada YD, Peng X, Chen M, Shah N, Suarez-Farinas M, Pavel AB, Nograles K, Guttman-Yassky E. Simpson EL, et al. Among authors: malik k. J Invest Dermatol. 2019 May;139(5):1063-1072. doi: 10.1016/j.jid.2018.10.043. Epub 2018 Dec 5. J Invest Dermatol. 2019. PMID: 30528828 Free article. Clinical Trial.
Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis.
Zhou L, Leonard A, Pavel AB, Malik K, Raja A, Glickman J, Estrada YD, Peng X, Del Duca E, Sanz-Cabanillas J, Ruano J, Xu H, Zhang N, Wen HC, Gonzalez J, Garcet S, Krueger JG, Guttman-Yassky E. Zhou L, et al. Among authors: malik k. J Allergy Clin Immunol. 2019 Jul;144(1):144-156. doi: 10.1016/j.jaci.2019.01.015. Epub 2019 Jan 24. J Allergy Clin Immunol. 2019. PMID: 30685456 Free article.
The blood proteomic signature of early-onset pediatric atopic dermatitis shows systemic inflammation and is distinct from adult long-standing disease.
Brunner PM, He H, Pavel AB, Czarnowicki T, Lefferdink R, Erickson T, Canter T, Puar N, Rangel SM, Malik K, Estrada Y, Krueger JG, Guttman-Yassky E, Paller AS. Brunner PM, et al. Among authors: malik k. J Am Acad Dermatol. 2019 Aug;81(2):510-519. doi: 10.1016/j.jaad.2019.04.036. Epub 2019 Apr 19. J Am Acad Dermatol. 2019. PMID: 31009665
Baseline IL-22 expression in patients with atopic dermatitis stratifies tissue responses to fezakinumab.
Brunner PM, Pavel AB, Khattri S, Leonard A, Malik K, Rose S, Jim On S, Vekaria AS, Traidl-Hoffmann C, Singer GK, Baum D, Gilleaudeau P, Sullivan-Whalen M, Fuentes-Duculan J, Li X, Zheng X, Estrada Y, Garcet S, Wen HC, Gonzalez J, Coats I, Cueto I, Neumann AU, Lebwohl MG, Krueger JG, Guttman-Yassky E. Brunner PM, et al. Among authors: malik k. J Allergy Clin Immunol. 2019 Jan;143(1):142-154. doi: 10.1016/j.jaci.2018.07.028. Epub 2018 Aug 17. J Allergy Clin Immunol. 2019. PMID: 30121291 Clinical Trial.
Dust mite induces multiple polar T cell axes in human skin.
Malik K, Ungar B, Garcet S, Dutt R, Dickstein D, Zheng X, Xu H, Estrada YD, Suárez-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E. Malik K, et al. Clin Exp Allergy. 2017 Dec;47(12):1648-1660. doi: 10.1111/cea.13040. Epub 2017 Nov 6. Clin Exp Allergy. 2017. PMID: 28977706
1,045 results