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Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2.
Miluzio A, Cuomo A, Cordiglieri C, Donnici L, Pesce E, Bombaci M, Conti M, Fasciani A, Terracciano L, Manganaro L, Toccafondi M, Scagliola A, Oliveto S, Ricciardi S, Grifantini R, De Francesco R, Abrignani S, Manfrini N, Biffo S. Miluzio A, et al. Among authors: fasciani a. EBioMedicine. 2023 Jan;87:104390. doi: 10.1016/j.ebiom.2022.104390. Epub 2022 Dec 28. EBioMedicine. 2023. PMID: 36584595 Free PMC article.
Typical NF2 and LTZR1 mutations are retained in an immortalized human schwann cell model of schwannomatosis.
Melfi V, Mohamed T, Colciago A, Fasciani A, De Francesco R, Bettio D, Cerqua C, Boaretto F, Basso E, Ferraresi S, Montini M, Eoli M, Papi L, Trevisson E, Magnaghi V. Melfi V, et al. Among authors: fasciani a. Heliyon. 2024 Oct 4;10(19):e38957. doi: 10.1016/j.heliyon.2024.e38957. eCollection 2024 Oct 15. Heliyon. 2024. PMID: 39444403 Free PMC article.
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution.
Conforti P, Bocchi VD, Campus I, Scaramuzza L, Galimberti M, Lischetti T, Talpo F, Pedrazzoli M, Murgia A, Ferrari I, Cordiglieri C, Fasciani A, Arenas E, Felsenfeld D, Biella G, Besusso D, Cattaneo E. Conforti P, et al. Among authors: fasciani a. Cell Rep Methods. 2022 Dec 19;2(12):100367. doi: 10.1016/j.crmeth.2022.100367. eCollection 2022 Dec 19. Cell Rep Methods. 2022. PMID: 36590694 Free PMC article.
Author Correction: MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.
Poli V, Fagnocchi L, Fasciani A, Cherubini A, Mazzoleni S, Ferrillo S, Miluzio A, Gaudioso G, Vaira V, Turdo A, Gaggianesi M, Chinnici A, Lipari E, Bicciato S, Bosari S, Todaro M, Zippo A. Poli V, et al. Among authors: fasciani a. Nat Commun. 2018 Sep 20;9(1):3921. doi: 10.1038/s41467-018-06480-y. Nat Commun. 2018. PMID: 30237396 Free PMC article.
MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome.
Fasciani A, D'Annunzio S, Poli V, Fagnocchi L, Beyes S, Michelatti D, Corazza F, Antonelli L, Gregoretti F, Oliva G, Belli R, Peroni D, Domenici E, Zambrano S, Intartaglia D, Settembre C, Conte I, Testi C, Vergyris P, Ruocco G, Zippo A. Fasciani A, et al. Nat Genet. 2020 Dec;52(12):1397-1411. doi: 10.1038/s41588-020-00724-8. Epub 2020 Nov 9. Nat Genet. 2020. PMID: 33169020 Free PMC article.
A millifluidic bioreactor allows the long term culture of primary lymphocytes or CD34+ hematopoietic cells while allowing the detection of tumorigenic expansion.
Ritter P, Oliveto S, Cordiglieri C, Fasciani A, Di Buduo CA, Della Volpe L, Bocconi A, Conci C, Miguel CP, Di Micco R, Balduini A, Raimondi MT, Biffo S. Ritter P, et al. Among authors: fasciani a. Front Bioeng Biotechnol. 2024 Oct 2;12:1388312. doi: 10.3389/fbioe.2024.1388312. eCollection 2024. Front Bioeng Biotechnol. 2024. PMID: 39416278 Free PMC article.
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring.
Sessa A, Fagnocchi L, Mastrototaro G, Massimino L, Zaghi M, Indrigo M, Cattaneo S, Martini D, Gabellini C, Pucci C, Fasciani A, Belli R, Taverna S, Andreazzoli M, Zippo A, Broccoli V. Sessa A, et al. Among authors: fasciani a. Neuron. 2019 Oct 23;104(2):271-289.e13. doi: 10.1016/j.neuron.2019.07.013. Epub 2019 Sep 9. Neuron. 2019. PMID: 31515109 Free article.
29 results