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Efficient base editing for multiple genes and loci in pigs using base editors.
Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Xie J, et al. Among authors: lan t. Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8. Nat Commun. 2019. PMID: 31253764 Free PMC article.
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems.
Wu H, Liu Q, Shi H, Xie J, Zhang Q, Ouyang Z, Li N, Yang Y, Liu Z, Zhao Y, Lai C, Ruan D, Peng J, Ge W, Chen F, Fan N, Jin Q, Liang Y, Lan T, Yang X, Wang X, Lei Z, Doevendans PA, Sluijter JPG, Wang K, Li X, Lai L. Wu H, et al. Among authors: lan t. Cell Mol Life Sci. 2018 Oct;75(19):3593-3607. doi: 10.1007/s00018-018-2810-3. Epub 2018 Apr 10. Cell Mol Life Sci. 2018. PMID: 29637228 Free PMC article.
Generation of a genetically modified pig model with CREBRFR457Q variant.
Li Y, Wang H, Chen H, Liao Y, Gou S, Yan Q, Zhuang Z, Li H, Wang J, Suo Y, Lan T, Liu Y, Zhao Y, Zou Q, Nie T, Hui X, Lai L, Wu D, Fan N. Li Y, et al. Among authors: lan t. FASEB J. 2022 Nov;36(11):e22611. doi: 10.1096/fj.202201117. FASEB J. 2022. PMID: 36250915
Cre-dependent Cas9-expressing pigs enable efficient in vivo genome editing.
Wang K, Jin Q, Ruan D, Yang Y, Liu Q, Wu H, Zhou Z, Ouyang Z, Liu Z, Zhao Y, Zhao B, Zhang Q, Peng J, Lai C, Fan N, Liang Y, Lan T, Li N, Wang X, Wang X, Fan Y, Doevendans PA, Sluijter JPG, Liu P, Li X, Lai L. Wang K, et al. Among authors: lan t. Genome Res. 2017 Dec;27(12):2061-2071. doi: 10.1101/gr.222521.117. Epub 2017 Nov 16. Genome Res. 2017. PMID: 29146772 Free PMC article.
Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs.
Yang Y, Wu H, Kang X, Liang Y, Lan T, Li T, Tan T, Peng J, Zhang Q, An G, Liu Y, Yu Q, Ma Z, Lian Y, Soh BS, Chen Q, Liu P, Chen Y, Sun X, Li R, Zhen X, Liu P, Yu Y, Li X, Fan Y. Yang Y, et al. Among authors: lan t. Protein Cell. 2018 Mar;9(3):283-297. doi: 10.1007/s13238-017-0499-y. Epub 2018 Jan 9. Protein Cell. 2018. PMID: 29318513 Free PMC article.
2,000 results