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Page 1
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Among authors: huiskonen jt. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
Community recommendations on cryoEM data archiving and validation.
Kleywegt GJ, Adams PD, Butcher SJ, Lawson CL, Rohou A, Rosenthal PB, Subramaniam S, Topf M, Abbott S, Baldwin PR, Berrisford JM, Bricogne G, Choudhary P, Croll TI, Danev R, Ganesan SJ, Grant T, Gutmanas A, Henderson R, Heymann JB, Huiskonen JT, Istrate A, Kato T, Lander GC, Lok SM, Ludtke SJ, Murshudov GN, Pye R, Pintilie GD, Richardson JS, Sachse C, Salih O, Scheres SHW, Schroeder GF, Sorzano COS, Stagg SM, Wang Z, Warshamanage R, Westbrook JD, Winn MD, Young JY, Burley SK, Hoch JC, Kurisu G, Morris K, Patwardhan A, Velankar S. Kleywegt GJ, et al. Among authors: huiskonen jt. IUCrJ. 2024 Mar 1;11(Pt 2):140-151. doi: 10.1107/S2052252524001246. IUCrJ. 2024. PMID: 38358351 Free PMC article.
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Grieben M, Pike AC, Shintre CA, Venturi E, El-Ajouz S, Tessitore A, Shrestha L, Mukhopadhyay S, Mahajan P, Chalk R, Burgess-Brown NA, Sitsapesan R, Huiskonen JT, Carpenter EP. Grieben M, et al. Among authors: huiskonen jt. Nat Struct Mol Biol. 2017 Feb;24(2):114-122. doi: 10.1038/nsmb.3343. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991905
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2.
Wilkes M, Madej MG, Kreuter L, Rhinow D, Heinz V, De Sanctis S, Ruppel S, Richter RM, Joos F, Grieben M, Pike AC, Huiskonen JT, Carpenter EP, Kühlbrandt W, Witzgall R, Ziegler C. Wilkes M, et al. Among authors: huiskonen jt. Nat Struct Mol Biol. 2017 Feb;24(2):123-130. doi: 10.1038/nsmb.3357. Epub 2017 Jan 16. Nat Struct Mol Biol. 2017. PMID: 28092368
Signal peptide mimicry primes Sec61 for client-selective inhibition.
Rehan S, Tranter D, Sharp PP, Craven GB, Lowe E, Anderl JL, Muchamuel T, Abrishami V, Kuivanen S, Wenzell NA, Jennings A, Kalyanaraman C, Strandin T, Javanainen M, Vapalahti O, Jacobson MP, McMinn D, Kirk CJ, Huiskonen JT, Taunton J, Paavilainen VO. Rehan S, et al. Among authors: huiskonen jt. Nat Chem Biol. 2023 Sep;19(9):1054-1062. doi: 10.1038/s41589-023-01326-1. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169961 Free PMC article.
Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.
Karki S, Javanainen M, Rehan S, Tranter D, Kellosalo J, Huiskonen JT, Happonen L, Paavilainen V. Karki S, et al. Among authors: huiskonen jt. EMBO Rep. 2023 Dec 6;24(12):e57910. doi: 10.15252/embr.202357910. Epub 2023 Nov 20. EMBO Rep. 2023. PMID: 37983950 Free PMC article.
Structure and interactions of the endogenous human Commander complex.
Laulumaa S, Kumpula EP, Huiskonen JT, Varjosalo M. Laulumaa S, et al. Among authors: huiskonen jt. Nat Struct Mol Biol. 2024 Jun;31(6):925-938. doi: 10.1038/s41594-024-01246-1. Epub 2024 Mar 8. Nat Struct Mol Biol. 2024. PMID: 38459129 Free PMC article.
90 results