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Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma.
Odeniyide P, Yohe ME, Pollard K, Vaseva AV, Calizo A, Zhang L, Rodriguez FJ, Gross JM, Allen AN, Wan X, Somwar R, Schreck KC, Kessler L, Wang J, Pratilas CA. Odeniyide P, et al. Among authors: pollard k. Oncogene. 2022 May;41(21):2973-2983. doi: 10.1038/s41388-022-02305-x. Epub 2022 Apr 22. Oncogene. 2022. PMID: 35459782 Free PMC article.
A clinically and genomically annotated nerve sheath tumor biospecimen repository.
Pollard K, Banerjee J, Doan X, Wang J, Guo X, Allaway R, Langmead S, Slobogean B, Meyer CF, Loeb DM, Morris CD, Belzberg AJ, Blakeley JO, Rodriguez FJ, Guinney J, Gosline SJC, Pratilas CA. Pollard K, et al. Sci Data. 2020 Jun 19;7(1):184. doi: 10.1038/s41597-020-0508-5. Sci Data. 2020. PMID: 32561749 Free PMC article.
Chromosome 8 gain is associated with high-grade transformation in MPNST.
Dehner C, Moon CI, Zhang X, Zhou Z, Miller C, Xu H, Wan X, Yang K, Mashl J, Gosline SJ, Wang Y, Zhang X, Godec A, Jones PA, Dahiya S, Bhatia H, Primeau T, Li S, Pollard K, Rodriguez FJ, Ding L, Pratilas CA, Shern JF, Hirbe AC. Dehner C, et al. Among authors: pollard k. JCI Insight. 2021 Mar 22;6(6):e146351. doi: 10.1172/jci.insight.146351. JCI Insight. 2021. PMID: 33591953 Free PMC article.
Detection of malignant peripheral nerve sheath tumors in patients with neurofibromatosis using aneuploidy and mutation identification in plasma.
Mattox AK, Douville C, Silliman N, Ptak J, Dobbyn L, Schaefer J, Popoli M, Blair C, Judge K, Pollard K, Pratilas C, Blakeley J, Rodriguez F, Papadopoulos N, Belzberg A, Bettegowda C. Mattox AK, et al. Among authors: pollard k. Elife. 2022 Mar 4;11:e74238. doi: 10.7554/eLife.74238. Elife. 2022. PMID: 35244537 Free PMC article.
Single-cell multiomics identifies clinically relevant mesenchymal stem-like cells and key regulators for MPNST malignancy.
Wu LMN, Zhang F, Rao R, Adam M, Pollard K, Szabo S, Liu X, Belcher KA, Luo Z, Ogurek S, Reilly C, Zhou X, Zhang L, Rubin J, Chang LS, Xin M, Yu J, Suva M, Pratilas CA, Potter S, Lu QR. Wu LMN, et al. Among authors: pollard k. Sci Adv. 2022 Nov 4;8(44):eabo5442. doi: 10.1126/sciadv.abo5442. Epub 2022 Nov 2. Sci Adv. 2022. PMID: 36322658 Free PMC article.
CDK4/6 inhibition enhances SHP2 inhibitor efficacy and is dependent upon restoration of RB function in malignant peripheral nerve sheath tumors.
Wang J, Calizo A, Zhang L, Pino JC, Lyu Y, Pollard K, Zhang X, Larsson AT, Conniff E, Llosa N, Wood DK, Largaespada DA, Moody SE, Gosline SJ, Hirbe AC, Pratilas CA. Wang J, et al. Among authors: pollard k. bioRxiv [Preprint]. 2023 Feb 3:2023.02.02.526674. doi: 10.1101/2023.02.02.526674. bioRxiv. 2023. Update in: Sci Adv. 2023 Nov 24;9(47):eadg8876. doi: 10.1126/sciadv.adg8876 PMID: 36778419 Free PMC article. Updated. Preprint.
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