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SARS-CoV-2 infection of human-induced pluripotent stem cells-derived lung lineage cells evokes inflammatory and chemosensory responses by targeting mitochondrial pathways.
Surendran H, Kumar S, Narasimhaiah S, Ananthamurthy A, Varghese PS, D'Souza GA, Medigeshi G, Pal R. Surendran H, et al. Among authors: medigeshi g. J Cell Physiol. 2022 Jul;237(7):2913-2928. doi: 10.1002/jcp.30755. Epub 2022 Apr 23. J Cell Physiol. 2022. PMID: 35460571 Free PMC article.
Oxidative stress specifically inhibits replication of dengue virus.
Khan NA, Kar M, Panwar A, Wangchuk J, Kumar S, Das A, Pandey AK, Lodha R, Medigeshi GR. Khan NA, et al. J Gen Virol. 2021 Apr;102(4):10.1099/jgv.0.001596. doi: 10.1099/jgv.0.001596. J Gen Virol. 2021. PMID: 33904816 Free PMC article.
Neutralizing antibodies from prior exposure to dengue virus negatively correlate with viremia on re-infection.
Anantharaj A, Agrawal T, Shashi PK, Tripathi A, Kumar P, Khan I, Pareek M, Singh B, Pattabiraman C, Kumar S, Pandey R, Chandele A, Lodha R, Whitehead SS, Medigeshi GR. Anantharaj A, et al. Among authors: medigeshi gr. Commun Med (Lond). 2023 Oct 19;3(1):148. doi: 10.1038/s43856-023-00378-7. Commun Med (Lond). 2023. PMID: 37857747 Free PMC article.
Effectiveness of ChAdOx1 nCoV-19 vaccine against SARS-CoV-2 infection during the delta (B.1.617.2) variant surge in India: a test-negative, case-control study and a mechanistic study of post-vaccination immune responses.
Thiruvengadam R, Awasthi A, Medigeshi G, Bhattacharya S, Mani S, Sivasubbu S, Shrivastava T, Samal S, Rathna Murugesan D, Koundinya Desiraju B, Kshetrapal P, Pandey R, Scaria V, Kumar Malik P, Taneja J, Binayke A, Vohra T, Zaheer A, Rathore D, Ahmad Khan N, Shaman H, Ahmed S, Kumar R, Deshpande S, Subramani C, Wadhwa N, Gupta N, Pandey AK, Bhattacharya J, Agrawal A, Vrati S, Bhatnagar S, Garg PK; Department of Biotechnology India Consortium for COVID-19 research. Thiruvengadam R, et al. Among authors: medigeshi g. Lancet Infect Dis. 2022 Apr;22(4):473-482. doi: 10.1016/S1473-3099(21)00680-0. Epub 2021 Nov 25. Lancet Infect Dis. 2022. PMID: 34838183 Free PMC article.
Sub-optimal neutralisation of omicron (B.1.1.529) variant by antibodies induced by vaccine alone or SARS-CoV-2 Infection plus vaccine (hybrid immunity) post 6-months.
Medigeshi GR, Batra G, Murugesan DR, Thiruvengadam R, Chattopadhyay S, Das B, Gosain M, Ayushi, Singh J, Anbalagan A, Shaman H, Pargai K, Mehdi F, Das SJ, Kahlon N, Singh S, Kshetrapal P, Wadhwa N, Pandey AK, Bhatnagar S, Garg PK. Medigeshi GR, et al. EBioMedicine. 2022 Apr;78:103938. doi: 10.1016/j.ebiom.2022.103938. Epub 2022 Mar 16. EBioMedicine. 2022. PMID: 35305396 Free PMC article.
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