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Loss of voltage-gated hydrogen channel 1 expression reveals heterogeneous metabolic adaptation to intracellular acidification by T cells.
Coe D, Poobalasingam T, Fu H, Bonacina F, Wang G, Morales V, Moregola A, Mitro N, Cheung KC, Ward EJ, Nadkarni S, Aksentijevic D, Bianchi K, Norata GD, Capasso M, Marelli-Berg FM. Coe D, et al. Among authors: morales v. JCI Insight. 2022 May 23;7(10):e147814. doi: 10.1172/jci.insight.147814. JCI Insight. 2022. PMID: 35472029 Free PMC article.
Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy.
Fernandez-Caggiano M, Kamynina A, Francois AA, Prysyazhna O, Eykyn TR, Krasemann S, Crespo-Leiro MG, Vieites MG, Bianchi K, Morales V, Domenech N, Eaton P. Fernandez-Caggiano M, et al. Among authors: morales v. Nat Metab. 2020 Nov;2(11):1223-1231. doi: 10.1038/s42255-020-00276-5. Epub 2020 Oct 26. Nat Metab. 2020. PMID: 33106688 Free PMC article.
The glucose transporter 2 regulates CD8+ T cell function via environment sensing.
Fu H, Vuononvirta J, Fanti S, Bonacina F, D'Amati A, Wang G, Poobalasingam T, Fankhaenel M, Lucchesi D, Coleby R, Tarussio D, Thorens B, Hearnden RJ, Longhi MP, Grevitt P, Sheikh MH, Solito E, Godinho SA, Bombardieri M, Smith DM, Cooper D, Iqbal AJ, Rathmell JC, Schaefer S, Morales V, Bianchi K, Norata GD, Marelli-Berg FM. Fu H, et al. Among authors: morales v. Nat Metab. 2023 Nov;5(11):1969-1985. doi: 10.1038/s42255-023-00913-9. Epub 2023 Oct 26. Nat Metab. 2023. PMID: 37884694 Free PMC article.
Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia.
Mian SA, Philippe C, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D, Morales V, Finch AJ, D'Alessandro A, Bianchi K, Wang J, Gallipoli P, Kordasti S, Kubasch AS, Cross M, Platzbecker U, Wiseman DH, Bonnet D, Bernard DG, Gribben JG, Rouault-Pierre K. Mian SA, et al. Among authors: morales v. Sci Transl Med. 2023 Mar;15(685):eabn5135. doi: 10.1126/scitranslmed.abn5135. Epub 2023 Mar 1. Sci Transl Med. 2023. PMID: 36857430 Free PMC article.
AMPK is a mechano-metabolic sensor linking cell adhesion and mitochondrial dynamics to Myosin-dependent cell migration.
Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V. Crosas-Molist E, et al. Among authors: morales v. Nat Commun. 2023 May 22;14(1):2740. doi: 10.1038/s41467-023-38292-0. Nat Commun. 2023. PMID: 37217519 Free PMC article.
Myocardial alterations following traumatic hemorrhagic injury.
Simpson R, Praditsuktavorn B, Wall J, Morales V, Thiemermann C, Tremoleda JL, Brohi K. Simpson R, et al. Among authors: morales v. J Trauma Acute Care Surg. 2023 Oct 1;95(4):481-489. doi: 10.1097/TA.0000000000003987. Epub 2023 May 29. J Trauma Acute Care Surg. 2023. PMID: 37249511
Artificial enforcement of the unfolded protein response (UPR) reduces disease features in multiple preclinical models of ALS/FTD.
Valenzuela V, Becerra D, Astorga JI, Fuentealba M, Diaz G, Bargsted L, Chacón C, Martinez A, Gozalvo R, Jackson K, Morales V, Heras ML, Tamburini G, Petrucelli L, Sardi P, Plate L, Hetz C. Valenzuela V, et al. Among authors: morales v. Mol Ther. 2025 Jan 10:S1525-0016(25)00008-5. doi: 10.1016/j.ymthe.2025.01.004. Online ahead of print. Mol Ther. 2025. PMID: 39799393
291 results