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IL-25 blockade augments antiviral immunity during respiratory virus infection.
Williams TC, Loo SL, Nichol KS, Reid AT, Veerati PC, Esneau C, Wark PAB, Grainge CL, Knight DA, Vincent T, Jackson CL, Alton K, Shimkets RA, Girkin JL, Bartlett NW. Williams TC, et al. Among authors: loo sl. Commun Biol. 2022 May 4;5(1):415. doi: 10.1038/s42003-022-03367-z. Commun Biol. 2022. PMID: 35508632 Free PMC article.
Recent advances in understanding and managing asthma.
Loo SL, Wark PA. Loo SL, et al. F1000Res. 2016 Aug 23;5:F1000 Faculty Rev-2052. doi: 10.12688/f1000research.9236.1. eCollection 2016. F1000Res. 2016. PMID: 27610226 Free PMC article. Review.
Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations.
Singanayagam A, Glanville N, Girkin JL, Ching YM, Marcellini A, Porter JD, Toussaint M, Walton RP, Finney LJ, Aniscenko J, Zhu J, Trujillo-Torralbo MB, Calderazzo MA, Grainge C, Loo SL, Veerati PC, Pathinayake PS, Nichol KS, Reid AT, James PL, Solari R, Wark PAB, Knight DA, Moffatt MF, Cookson WO, Edwards MR, Mallia P, Bartlett NW, Johnston SL. Singanayagam A, et al. Among authors: loo sl. Nat Commun. 2018 Jun 8;9(1):2229. doi: 10.1038/s41467-018-04574-1. Nat Commun. 2018. PMID: 29884817 Free PMC article.
Antiviral immunity is impaired in COPD patients with frequent exacerbations.
Singanayagam A, Loo SL, Calderazzo M, Finney LJ, Trujillo Torralbo MB, Bakhsoliani E, Girkin J, Veerati P, Pathinayake PS, Nichol KS, Reid A, Footitt J, Wark PAB, Grainge CL, Johnston SL, Bartlett NW, Mallia P. Singanayagam A, et al. Among authors: loo sl. Am J Physiol Lung Cell Mol Physiol. 2019 Dec 1;317(6):L893-L903. doi: 10.1152/ajplung.00253.2019. Epub 2019 Sep 12. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31513433 Free PMC article.
Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon.
Finney LJ, Glanville N, Farne H, Aniscenko J, Fenwick P, Kemp SV, Trujillo-Torralbo MB, Loo SL, Calderazzo MA, Wedzicha JA, Mallia P, Bartlett NW, Johnston SL, Singanayagam A. Finney LJ, et al. Among authors: loo sl. J Allergy Clin Immunol. 2021 Feb;147(2):510-519.e5. doi: 10.1016/j.jaci.2020.09.034. Epub 2020 Oct 15. J Allergy Clin Immunol. 2021. PMID: 33068560 Free PMC article.
Rhinovirus-induced CCL17 and CCL22 in Asthma Exacerbations and Differential Regulation by STAT6.
Williams TC, Jackson DJ, Maltby S, Walton RP, Ching YM, Glanville N, Singanayagam A, Brewins JJ, Clarke D, Hirsman AG, Loo SL, Wei L, Beale JE, Casolari P, Caramori G, Papi A, Belvisi M, Wark PAB, Johnston SL, Edwards MR, Bartlett NW. Williams TC, et al. Among authors: loo sl. Am J Respir Cell Mol Biol. 2021 Mar;64(3):344-356. doi: 10.1165/rcmb.2020-0011OC. Am J Respir Cell Mol Biol. 2021. PMID: 33264064 Free PMC article. Clinical Trial.
TLR2-mediated innate immune priming boosts lung anti-viral immunity.
Girkin J, Loo SL, Esneau C, Maltby S, Mercuri F, Chua B, Reid AT, Veerati PC, Grainge CL, Wark PAB, Knight D, Jackson D, Demaison C, Bartlett NW. Girkin J, et al. Among authors: loo sl. Eur Respir J. 2021 Jul 1;58(1):2001584. doi: 10.1183/13993003.01584-2020. Print 2021 Jul. Eur Respir J. 2021. PMID: 33303547 Free article.
37 results