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Human adipose-derived mesenchymal stem cells prevent type 1 diabetes induced by immune checkpoint blockade.
Kawada-Horitani E, Kita S, Okita T, Nakamura Y, Nishida H, Honma Y, Fukuda S, Tsugawa-Shimizu Y, Kozawa J, Sakaue T, Kawachi Y, Fujishima Y, Nishizawa H, Azuma M, Maeda N, Shimomura I. Kawada-Horitani E, et al. Among authors: okita t. Diabetologia. 2022 Jul;65(7):1185-1197. doi: 10.1007/s00125-022-05708-3. Epub 2022 May 5. Diabetologia. 2022. PMID: 35511238 Free PMC article.
Effective waist circumference reduction rate necessary to avoid the development of type 2 diabetes in Japanese men with abdominal obesity.
Kashiwagi R, Iwahashi H, Yamada Y, Sakaue T, Okita T, Kawachi Y, Iwamoto R, Saisho K, Tamba S, Yamamoto K, Watanabe T, Fujimoto T, Matsuzawa Y. Kashiwagi R, et al. Among authors: okita t. Endocr J. 2017 Sep 30;64(9):881-894. doi: 10.1507/endocrj.EJ17-0113. Epub 2017 Jul 15. Endocr J. 2017. PMID: 28717063 Free article.
A disintegrin and metalloproteinase 12 prevents heart failure by regulating cardiac hypertrophy and fibrosis.
Nakamura Y, Kita S, Tanaka Y, Fukuda S, Obata Y, Okita T, Kawachi Y, Tsugawa-Shimizu Y, Fujishima Y, Nishizawa H, Miyagawa S, Sawa Y, Sehara-Fujisawa A, Maeda N, Shimomura I. Nakamura Y, et al. Among authors: okita t. Am J Physiol Heart Circ Physiol. 2020 Feb 1;318(2):H238-H251. doi: 10.1152/ajpheart.00496.2019. Epub 2019 Nov 27. Am J Physiol Heart Circ Physiol. 2020. PMID: 31774689 Free article.
Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice.
Nakamura Y, Kita S, Tanaka Y, Fukuda S, Obata Y, Okita T, Nishida H, Takahashi Y, Kawachi Y, Tsugawa-Shimizu Y, Fujishima Y, Nishizawa H, Takakura Y, Miyagawa S, Sawa Y, Maeda N, Shimomura I. Nakamura Y, et al. Among authors: okita t. Mol Ther. 2020 Oct 7;28(10):2203-2219. doi: 10.1016/j.ymthe.2020.06.026. Epub 2020 Jul 10. Mol Ther. 2020. PMID: 32652045 Free PMC article.
Increased vascular permeability and severe renal tubular damage after ischemia-reperfusion injury in mice lacking adiponectin or T-cadherin.
Tsugawa-Shimizu Y, Fujishima Y, Kita S, Minami S, Sakaue TA, Nakamura Y, Okita T, Kawachi Y, Fukada S, Namba-Hamano T, Takabatake Y, Isaka Y, Nishizawa H, Ranscht B, Maeda N, Shimomura I. Tsugawa-Shimizu Y, et al. Among authors: okita t. Am J Physiol Endocrinol Metab. 2021 Feb 1;320(2):E179-E190. doi: 10.1152/ajpendo.00393.2020. Epub 2020 Dec 7. Am J Physiol Endocrinol Metab. 2021. PMID: 33284092 Free PMC article.
Chronic hyperadiponectinemia induced by transgenic overexpression increases plasma exosomes without significantly improving glucose and lipid metabolism.
Kawada K, Kita S, Fukuda S, Fukuoka K, Okita T, Kawada-Horitani E, Iioka M, Sakaue TA, Kawachi Y, Fujii K, Kimura Y, Otabe S, Fujishima Y, Nishizawa H, Maeda N, Shimomura I. Kawada K, et al. Among authors: okita t. Endocr J. 2023 Jun 28;70(6):635-645. doi: 10.1507/endocrj.EJ22-0665. Epub 2023 Apr 15. Endocr J. 2023. PMID: 37062722 Free article.
Pharmacological HIF-1 activation upregulates extracellular vesicle production synergistically with adiponectin through transcriptional induction and protein stabilization of T-cadherin.
Fujii K, Fujishima Y, Kita S, Kawada K, Fukuoka K, Sakaue TA, Okita T, Kawada-Horitani E, Nagao H, Fukuda S, Maeda N, Nishizawa H, Shimomura I. Fujii K, et al. Among authors: okita t. Sci Rep. 2024 Feb 13;14(1):3620. doi: 10.1038/s41598-024-51935-6. Sci Rep. 2024. PMID: 38351156 Free PMC article.
Soluble T-cadherin secretion from endothelial cells is regulated via insulin/PI3K/Akt signalling.
Okita T, Kita S, Fukuda S, Kondo Y, Sakaue TA, Iioka M, Fukuoka K, Kawada K, Nagao H, Obata Y, Fujishima Y, Ebihara T, Matsumoto H, Nakagawa S, Kimura T, Nishizawa H, Shimomura I. Okita T, et al. Biochem Biophys Res Commun. 2024 Nov 5;732:150403. doi: 10.1016/j.bbrc.2024.150403. Epub 2024 Jul 14. Biochem Biophys Res Commun. 2024. PMID: 39047402 Free article.
307 results